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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC44A2 All Species: 33.33
Human Site: Y280 Identified Species: 73.33
UniProt: Q8IWA5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWA5 NP_065161.3 706 80152 Y280 G Y G I F H C Y M E Y S R L R
Chimpanzee Pan troglodytes XP_001165902 706 80119 Y280 G Y G I F H C Y M E Y S R L R
Rhesus Macaque Macaca mulatta XP_001100446 717 81561 Y290 G Y G I W H C Y Q Q Y T N L Q
Dog Lupus familis XP_868166 704 79909 Y278 G Y G I F H C Y M E Y M R L R
Cat Felis silvestris
Mouse Mus musculus Q8BY89 704 79905 Y278 G Y G I F H C Y M E Y S R L R
Rat Rattus norvegicus B4F795 705 79878 Y280 G Y G I F H C Y A E Y S R L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426673 715 81291 Y286 G Y G T W H C Y W E Y D H L K
Frog Xenopus laevis Q6IP59 710 80675 Y284 G Y G I F H C Y M E Y A R L K
Zebra Danio Brachydanio rerio B0S5A7 700 79484 Y257 G Y G I W H C Y W E Y S S L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAP3 796 90611 F350 G L L V G I Y F S V K Q Y I H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20026 771 87293 W360 G F G A G F S W L K W N T L K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 54.1 93.6 N.A. 90.5 91.9 N.A. N.A. 63.7 76 60.9 N.A. 32 N.A. 37.7 N.A.
Protein Similarity: 100 100 73.2 95.8 N.A. 95.4 96.5 N.A. N.A. 79.4 88.5 77 N.A. 49.8 N.A. 57 N.A.
P-Site Identity: 100 100 60 93.3 N.A. 100 93.3 N.A. N.A. 60 86.6 73.3 N.A. 6.6 N.A. 20 N.A.
P-Site Similarity: 100 100 86.6 93.3 N.A. 100 93.3 N.A. N.A. 73.3 100 86.6 N.A. 26.6 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0 % E
% Phe: 0 10 0 0 55 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 100 0 91 0 19 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 82 0 0 0 0 0 0 10 0 10 % H
% Ile: 0 0 0 73 0 10 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 37 % K
% Leu: 0 10 10 0 0 0 0 0 10 0 0 0 0 91 0 % L
% Met: 0 0 0 0 0 0 0 0 46 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 10 0 10 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 46 % R
% Ser: 0 0 0 0 0 0 10 0 10 0 0 46 10 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 10 10 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 28 0 0 10 19 0 10 0 0 0 0 % W
% Tyr: 0 82 0 0 0 0 10 82 0 0 82 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _