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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPRIP All Species: 8.18
Human Site: T373 Identified Species: 20
UniProt: Q8IWB1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWB1 NP_203755.1 547 62060 T373 P R E P S E G T P A S S T D W
Chimpanzee Pan troglodytes XP_508022 708 79702 T534 P R E P S E G T P A S S T D W
Rhesus Macaque Macaca mulatta XP_001098687 528 60198 S364 P D Q E Q L T S V D W P E S F
Dog Lupus familis XP_852139 551 62555 A373 P R E P S G E A P A S S S D W
Cat Felis silvestris
Mouse Mus musculus Q3TNL8 555 63219 G376 P K E P C G G G P A S S A H W
Rat Rattus norvegicus Q66H52 547 62530 F381 Q A P E R E Q F T S V D W P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512434 561 64446 P371 P R G N P L A P P T S N T Y W
Chicken Gallus gallus XP_426536 506 58131 D328 P R N C L A A D L P S S T H W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q567X9 539 61344 S359 S H F P S D T S N S S D T H W
Tiger Blowfish Takifugu rubipres Q90XY5 534 60202 P361 P S G S E S P P D P Y W P L S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.9 31.2 86.2 N.A. 77.6 33.4 N.A. 67.9 54.1 N.A. 45.3 44.9 N.A. N.A. N.A. N.A.
Protein Similarity: 100 77.2 50 91.2 N.A. 84.6 52.2 N.A. 79.3 67 N.A. 65 65.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 73.3 N.A. 60 6.6 N.A. 40 40 N.A. 33.3 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 80 N.A. 66.6 13.3 N.A. 46.6 40 N.A. 53.3 6.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 20 10 0 40 0 0 10 0 0 % A
% Cys: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 10 0 10 10 10 0 20 0 30 0 % D
% Glu: 0 0 40 20 10 30 10 0 0 0 0 0 10 0 10 % E
% Phe: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 10 % F
% Gly: 0 0 20 0 0 20 30 10 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 30 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 20 0 0 10 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 10 0 0 10 0 0 0 % N
% Pro: 80 0 10 50 10 0 10 20 50 20 0 10 10 10 0 % P
% Gln: 10 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 50 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 0 10 40 10 0 20 0 20 70 50 10 10 10 % S
% Thr: 0 0 0 0 0 0 20 20 10 10 0 0 50 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 10 10 0 70 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _