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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPRIP
All Species:
18.18
Human Site:
Y521
Identified Species:
44.44
UniProt:
Q8IWB1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWB1
NP_203755.1
547
62060
Y521
R
K
T
L
D
S
F
Y
E
M
L
K
N
A
P
Chimpanzee
Pan troglodytes
XP_508022
708
79702
Y682
R
K
T
L
D
S
F
Y
E
M
L
K
N
A
P
Rhesus Macaque
Macaca mulatta
XP_001098687
528
60198
S503
V
L
N
P
K
A
H
S
Q
A
V
E
E
F
Q
Dog
Lupus familis
XP_852139
551
62555
Y521
R
K
T
V
D
A
F
Y
E
M
L
K
N
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TNL8
555
63219
Y524
R
N
T
V
D
S
F
Y
E
M
L
K
N
A
P
Rat
Rattus norvegicus
Q66H52
547
62530
F511
N
A
E
P
V
N
L
F
Q
H
L
V
L
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512434
561
64446
S519
R
K
T
V
D
S
F
S
E
M
L
K
N
T
S
Chicken
Gallus gallus
XP_426536
506
58131
H476
R
K
T
I
D
T
F
H
E
M
L
R
N
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q567X9
539
61344
E507
A
K
M
E
E
H
F
E
E
M
V
R
N
T
S
Tiger Blowfish
Takifugu rubipres
Q90XY5
534
60202
N506
A
Q
T
L
Q
H
F
N
E
M
L
K
N
A
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
31.2
86.2
N.A.
77.6
33.4
N.A.
67.9
54.1
N.A.
45.3
44.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.2
50
91.2
N.A.
84.6
52.2
N.A.
79.3
67
N.A.
65
65.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
86.6
13.3
N.A.
73.3
60
N.A.
33.3
66.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
33.3
N.A.
80
86.6
N.A.
53.3
73.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
0
0
20
0
0
0
10
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
10
0
0
10
80
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
80
10
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
20
10
10
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
60
0
0
10
0
0
0
0
0
0
60
0
0
0
% K
% Leu:
0
10
0
30
0
0
10
0
0
0
80
0
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
80
0
0
0
0
0
% M
% Asn:
10
10
10
0
0
10
0
10
0
0
0
0
80
10
0
% N
% Pro:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
60
% P
% Gln:
0
10
0
0
10
0
0
0
20
0
0
0
0
0
10
% Q
% Arg:
60
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% R
% Ser:
0
0
0
0
0
40
0
20
0
0
0
0
0
0
30
% S
% Thr:
0
0
70
0
0
10
0
0
0
0
0
0
0
30
0
% T
% Val:
10
0
0
30
10
0
0
0
0
0
20
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _