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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TEX2
All Species:
13.64
Human Site:
S345
Identified Species:
37.5
UniProt:
Q8IWB9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWB9
NP_060939.3
1127
125303
S345
L
E
S
N
N
N
Y
S
I
K
E
E
E
C
D
Chimpanzee
Pan troglodytes
XP_001160311
1127
125374
S345
L
E
S
N
N
N
Y
S
I
K
E
E
E
C
D
Rhesus Macaque
Macaca mulatta
XP_001116521
1127
125517
S345
L
E
S
N
N
N
Y
S
I
K
E
E
E
C
D
Dog
Lupus familis
XP_850455
1138
126318
K345
S
N
N
N
Y
S
I
K
E
E
E
C
D
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPJ0
1128
125207
K345
E
S
N
N
Y
S
I
K
E
E
E
G
D
S
E
Rat
Rattus norvegicus
XP_001081602
1129
125119
I345
L
E
S
N
N
Y
S
I
K
E
E
E
G
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510414
1121
125057
K345
S
N
N
N
Y
S
I
K
E
E
E
C
D
S
E
Chicken
Gallus gallus
XP_415667
1216
136019
S438
L
E
S
N
N
N
Y
S
I
K
E
E
E
C
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495172
876
98659
A151
N
Q
N
L
I
D
P
A
D
P
S
D
P
F
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.4
91.9
N.A.
90
89.1
N.A.
79.8
69.1
N.A.
N.A.
N.A.
N.A.
N.A.
23
N.A.
Protein Similarity:
100
99.7
98.2
94.5
N.A.
94.5
93.3
N.A.
86.8
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
38.5
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
13.3
46.6
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
53.3
N.A.
46.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
23
0
45
0
% C
% Asp:
0
0
0
0
0
12
0
0
12
0
0
12
34
12
45
% D
% Glu:
12
56
0
0
0
0
0
0
34
45
89
56
45
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
34
12
45
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
34
12
45
0
0
0
0
0
% K
% Leu:
56
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
23
45
89
56
45
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
12
0
0
12
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
23
12
56
0
0
34
12
45
0
0
12
0
0
34
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
12
45
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _