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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM114A1
All Species:
13.64
Human Site:
T225
Identified Species:
33.33
UniProt:
Q8IWE2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWE2
NP_612398.1
563
60742
T225
N
T
G
K
S
V
L
T
G
G
L
D
A
L
E
Chimpanzee
Pan troglodytes
XP_517149
563
60761
T225
N
T
G
K
S
V
L
T
G
G
L
D
A
L
E
Rhesus Macaque
Macaca mulatta
XP_001092622
555
59830
T225
N
T
G
K
S
V
L
T
G
G
L
D
A
L
E
Dog
Lupus familis
XP_536261
566
61307
G231
G
K
S
V
L
T
G
G
L
D
A
L
E
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D281
569
60994
L225
Q
N
T
G
K
S
V
L
T
G
G
L
D
A
L
Rat
Rattus norvegicus
XP_573600
567
60739
L223
Q
N
T
G
K
S
V
L
T
G
G
L
D
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508403
585
63794
E197
K
T
M
D
V
I
A
E
G
D
P
G
F
K
K
Chicken
Gallus gallus
XP_423859
561
60945
S220
N
T
G
K
S
V
L
S
G
G
L
D
A
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082947
546
59444
D197
S
V
I
T
G
G
L
D
A
L
E
F
I
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624064
469
52877
F179
K
E
Q
S
S
F
G
F
G
N
L
I
S
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95
82.3
N.A.
77.3
77.7
N.A.
32.6
63.7
N.A.
53.4
N.A.
N.A.
27.3
N.A.
N.A.
Protein Similarity:
100
99.4
96.8
87.8
N.A.
83.4
83
N.A.
53.5
75.8
N.A.
69
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
6.6
6.6
N.A.
13.3
93.3
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
13.3
13.3
N.A.
26.6
100
N.A.
20
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
10
0
10
0
40
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
20
0
40
20
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
0
0
10
0
10
0
40
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
10
10
10
0
% F
% Gly:
10
0
40
20
10
10
20
10
60
60
20
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
10
10
0
10
% I
% Lys:
20
10
0
40
20
0
0
0
0
0
0
0
0
10
20
% K
% Leu:
0
0
0
0
10
0
50
20
10
10
50
30
0
40
20
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
20
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
20
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
50
20
0
10
0
0
0
0
10
10
0
% S
% Thr:
0
50
20
10
0
10
0
30
20
0
0
0
0
0
0
% T
% Val:
0
10
0
10
10
40
20
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _