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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM114A1 All Species: 33.94
Human Site: Y537 Identified Species: 82.96
UniProt: Q8IWE2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWE2 NP_612398.1 563 60742 Y537 E G C N S T T Y I Q D A F Q L
Chimpanzee Pan troglodytes XP_517149 563 60761 Y537 E G C N S T T Y I Q D A F Q L
Rhesus Macaque Macaca mulatta XP_001092622 555 59830 Y529 E G C N S T T Y I Q D A F Q L
Dog Lupus familis XP_536261 566 61307 Y540 E G C N S T T Y I Q D A F Q L
Cat Felis silvestris
Mouse Mus musculus Q9D281 569 60994 Y538 E G S N S T T Y V Q D A L Q L
Rat Rattus norvegicus XP_573600 567 60739 Y536 E G C N S T T Y V Q D A L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508403 585 63794 Y476 E A S N S A S Y V Q D A F Q L
Chicken Gallus gallus XP_423859 561 60945 Y535 E G C N S T T Y V Q D A F Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001082947 546 59444 Y512 E G S N S T T Y I H N A F Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624064 469 52877 M444 S N I T T I F M E A S N A S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95 82.3 N.A. 77.3 77.7 N.A. 32.6 63.7 N.A. 53.4 N.A. N.A. 27.3 N.A. N.A.
Protein Similarity: 100 99.4 96.8 87.8 N.A. 83.4 83 N.A. 53.5 75.8 N.A. 69 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 80 86.6 N.A. 66.6 93.3 N.A. 80 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 80 100 N.A. 86.6 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 0 0 10 0 90 10 0 0 % A
% Cys: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 % D
% Glu: 90 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 70 0 0 % F
% Gly: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 0 0 50 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 90 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 90 0 0 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 80 0 0 0 90 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 30 0 90 0 10 0 0 0 10 0 0 10 10 % S
% Thr: 0 0 0 10 10 80 80 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _