KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCUN1D3
All Species:
14.24
Human Site:
S292
Identified Species:
24.1
UniProt:
Q8IWE4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWE4
NP_775746.1
304
34291
S292
G
E
G
R
G
A
L
S
S
G
P
E
G
L
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105171
427
47916
N335
F
T
F
T
F
A
K
N
P
G
Q
K
G
L
D
Dog
Lupus familis
XP_547103
304
34198
S292
G
E
G
R
G
A
L
S
S
G
P
E
G
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0V2
304
34420
S292
V
E
G
R
G
T
L
S
S
G
Q
E
G
L
C
Rat
Rattus norvegicus
Q4V8B2
304
34332
S292
V
E
G
R
G
A
L
S
S
G
P
E
G
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508278
304
34214
P292
E
E
T
K
W
I
T
P
S
D
T
D
G
P
S
Chicken
Gallus gallus
Q5ZKU1
259
30091
R248
D
D
F
V
E
F
A
R
P
Q
I
A
G
T
K
Frog
Xenopus laevis
Q6DFA1
303
34608
C291
E
K
T
D
C
I
P
C
L
G
T
D
H
Q
S
Zebra Danio
Brachydanio rerio
Q5RHX6
280
32402
D268
G
A
W
P
V
L
L
D
E
F
V
E
W
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUQ8
288
33676
A276
S
Q
K
N
I
S
S
A
Y
Q
T
S
H
S
T
Honey Bee
Apis mellifera
XP_001120647
298
34001
I286
N
D
Q
M
N
Q
N
I
S
K
D
D
M
K
D
Nematode Worm
Caenorhab. elegans
Q9U3C8
295
34115
S284
Y
P
K
P
G
N
A
S
N
D
Q
Q
M
E
T
Sea Urchin
Strong. purpuratus
XP_782778
317
36164
E305
L
K
T
L
N
Q
V
E
K
E
D
N
N
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150184
250
29251
Y239
L
I
D
E
F
V
E
Y
L
T
E
N
G
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
30.9
97.3
N.A.
97.6
98
N.A.
83.5
32.2
76.6
26.9
N.A.
32.8
42.1
29.6
44.4
Protein Similarity:
100
N.A.
42.6
98
N.A.
98.3
99
N.A.
91.1
50.3
84.5
40.7
N.A.
47.7
56.2
46.3
59.9
P-Site Identity:
100
N.A.
26.6
100
N.A.
80
93.3
N.A.
20
6.6
6.6
20
N.A.
0
6.6
13.3
0
P-Site Similarity:
100
N.A.
40
100
N.A.
80
93.3
N.A.
33.3
13.3
20
20
N.A.
20
20
26.6
13.3
Percent
Protein Identity:
N.A.
33.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
50.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
29
15
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
29
% C
% Asp:
8
15
8
8
0
0
0
8
0
15
15
22
0
0
15
% D
% Glu:
15
36
0
8
8
0
8
8
8
8
8
36
0
8
8
% E
% Phe:
8
0
15
0
15
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
22
0
29
0
36
0
0
0
0
43
0
0
58
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
8
0
0
8
15
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
15
15
8
0
0
8
0
8
8
0
8
0
8
15
% K
% Leu:
15
0
0
8
0
8
36
0
15
0
0
0
0
43
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
8
0
0
8
15
8
8
8
8
0
0
15
8
0
0
% N
% Pro:
0
8
0
15
0
0
8
8
15
0
22
0
0
8
0
% P
% Gln:
0
8
8
0
0
15
0
0
0
15
22
8
0
15
0
% Q
% Arg:
0
0
0
29
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
8
36
43
0
0
8
0
8
15
% S
% Thr:
0
8
22
8
0
8
8
0
0
8
22
0
0
8
15
% T
% Val:
15
0
0
8
8
8
8
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _