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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCC2
All Species:
20
Human Site:
S1105
Identified Species:
40
UniProt:
Q8IWJ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWJ2
NP_055450.1
1583
184657
S1105
T
L
Q
E
E
I
T
S
L
Q
S
S
V
Q
Q
Chimpanzee
Pan troglodytes
XP_001135112
1735
200938
E1256
T
T
V
N
E
L
E
E
L
Q
V
Q
L
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531770
1814
209228
S1336
T
L
Q
E
E
M
T
S
L
Q
S
S
V
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHG3
1679
194426
S1197
T
L
Q
E
E
I
T
S
L
Q
S
S
V
Q
H
Rat
Rattus norvegicus
NP_001101103
1679
195065
S1197
T
L
Q
E
E
M
T
S
L
Q
S
S
V
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513561
594
68554
K130
Q
Y
E
E
K
N
T
K
I
K
Q
L
L
V
K
Chicken
Gallus gallus
XP_425585
1693
196021
S1215
T
L
Q
E
E
I
K
S
L
Q
S
T
M
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097755
1135
130104
S671
Q
V
K
D
A
V
H
S
K
Q
Q
A
L
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34562
660
75020
E196
L
T
K
A
L
Q
D
E
K
I
K
S
A
D
F
Sea Urchin
Strong. purpuratus
XP_794992
824
93860
E360
L
S
D
L
K
K
T
E
S
E
Q
R
S
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S2T0
788
89840
K324
L
Q
V
L
L
A
E
K
E
S
K
I
A
E
M
Baker's Yeast
Sacchar. cerevisiae
P31111
875
100016
E411
Q
Q
Y
E
D
I
K
E
N
L
E
Q
K
M
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
N.A.
72.4
N.A.
73.4
73
N.A.
32.2
57.8
N.A.
N.A.
N.A.
23.1
N.A.
20.9
22.7
Protein Similarity:
100
86.1
N.A.
79.6
N.A.
83.6
83.3
N.A.
34.5
74.1
N.A.
N.A.
N.A.
42.9
N.A.
31.6
36.9
P-Site Identity:
100
33.3
N.A.
93.3
N.A.
93.3
86.6
N.A.
13.3
73.3
N.A.
N.A.
N.A.
20
N.A.
6.6
6.6
P-Site Similarity:
100
53.3
N.A.
100
N.A.
93.3
93.3
N.A.
53.3
93.3
N.A.
N.A.
N.A.
60
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.8
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
0
0
0
0
0
9
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
9
0
9
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
9
59
50
0
17
34
9
9
9
0
0
9
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
0
0
0
34
0
0
9
9
0
9
0
0
0
% I
% Lys:
0
0
17
0
17
9
17
17
17
9
17
0
9
0
17
% K
% Leu:
25
42
0
17
17
9
0
0
50
9
0
9
25
0
0
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
9
9
9
% M
% Asn:
0
0
0
9
0
9
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
25
17
42
0
0
9
0
0
0
59
25
17
0
50
25
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
50
9
9
42
42
9
0
9
% S
% Thr:
50
17
0
0
0
0
50
0
0
0
0
9
0
9
0
% T
% Val:
0
9
17
0
0
9
0
0
0
0
9
0
34
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _