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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCC2
All Species:
13.94
Human Site:
S1466
Identified Species:
27.88
UniProt:
Q8IWJ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWJ2
NP_055450.1
1583
184657
S1466
E
L
V
Q
K
L
S
S
T
T
K
S
A
D
H
Chimpanzee
Pan troglodytes
XP_001135112
1735
200938
T1610
Q
L
K
N
E
P
T
T
R
S
P
V
S
S
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531770
1814
209228
S1697
E
L
V
Q
K
L
S
S
T
T
K
S
A
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHG3
1679
194426
E1558
F
T
K
E
E
L
A
E
K
L
S
S
T
T
K
Rat
Rattus norvegicus
NP_001101103
1679
195065
E1558
F
T
K
E
E
L
A
E
K
L
S
S
T
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513561
594
68554
T482
L
S
T
A
T
K
S
T
D
H
L
N
S
L
L
Chicken
Gallus gallus
XP_425585
1693
196021
T1576
E
L
I
E
K
L
S
T
T
T
K
S
A
D
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097755
1135
130104
L1023
V
K
H
L
T
A
L
L
A
E
N
E
Q
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34562
660
75020
V548
L
K
K
T
N
H
H
V
A
E
L
L
S
D
A
Sea Urchin
Strong. purpuratus
XP_794992
824
93860
D712
T
A
A
Q
H
R
I
D
H
F
T
E
I
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S2T0
788
89840
L676
T
Q
R
H
I
L
A
L
Q
E
E
I
E
E
L
Baker's Yeast
Sacchar. cerevisiae
P31111
875
100016
S763
N
F
T
K
P
S
D
S
P
K
K
N
A
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
N.A.
72.4
N.A.
73.4
73
N.A.
32.2
57.8
N.A.
N.A.
N.A.
23.1
N.A.
20.9
22.7
Protein Similarity:
100
86.1
N.A.
79.6
N.A.
83.6
83.3
N.A.
34.5
74.1
N.A.
N.A.
N.A.
42.9
N.A.
31.6
36.9
P-Site Identity:
100
6.6
N.A.
100
N.A.
13.3
13.3
N.A.
6.6
80
N.A.
N.A.
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
46.6
N.A.
100
N.A.
33.3
33.3
N.A.
26.6
100
N.A.
N.A.
N.A.
6.6
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.8
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
9
25
0
17
0
0
0
34
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
9
0
0
0
0
42
0
% D
% Glu:
25
0
0
25
25
0
0
17
0
25
9
17
9
9
0
% E
% Phe:
17
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
9
9
9
9
9
0
9
9
0
0
0
0
25
% H
% Ile:
0
0
9
0
9
0
9
0
0
0
0
9
9
0
0
% I
% Lys:
0
17
34
9
25
9
0
0
17
9
34
0
0
0
17
% K
% Leu:
17
34
0
9
0
50
9
17
0
17
17
9
0
9
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
9
0
0
0
0
0
9
17
0
0
0
% N
% Pro:
0
0
0
0
9
9
0
0
9
0
9
0
0
0
0
% P
% Gln:
9
9
0
25
0
0
0
0
9
0
0
0
9
0
9
% Q
% Arg:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
0
9
34
25
0
9
17
42
25
9
0
% S
% Thr:
17
17
17
9
17
0
9
25
25
25
9
0
17
34
9
% T
% Val:
9
0
17
0
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _