KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCC2
All Species:
4.55
Human Site:
T114
Identified Species:
9.09
UniProt:
Q8IWJ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWJ2
NP_055450.1
1583
184657
T114
T
T
D
E
K
K
E
T
V
T
Q
L
Q
N
I
Chimpanzee
Pan troglodytes
XP_001135112
1735
200938
T343
T
T
D
E
K
K
E
T
V
T
Q
L
Q
N
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531770
1814
209228
E348
A
T
N
E
K
E
Q
E
I
T
R
L
Q
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHG3
1679
194426
E214
T
S
D
E
K
Q
Q
E
I
I
H
L
Q
K
V
Rat
Rattus norvegicus
NP_001101103
1679
195065
E214
T
S
D
E
K
Q
Q
E
I
I
H
L
Q
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513561
594
68554
Chicken
Gallus gallus
XP_425585
1693
196021
E217
V
N
D
D
K
N
K
E
I
A
I
L
Q
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097755
1135
130104
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34562
660
75020
Sea Urchin
Strong. purpuratus
XP_794992
824
93860
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S2T0
788
89840
Baker's Yeast
Sacchar. cerevisiae
P31111
875
100016
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
N.A.
72.4
N.A.
73.4
73
N.A.
32.2
57.8
N.A.
N.A.
N.A.
23.1
N.A.
20.9
22.7
Protein Similarity:
100
86.1
N.A.
79.6
N.A.
83.6
83.3
N.A.
34.5
74.1
N.A.
N.A.
N.A.
42.9
N.A.
31.6
36.9
P-Site Identity:
100
100
N.A.
40
N.A.
40
40
N.A.
0
26.6
N.A.
N.A.
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
N.A.
80
N.A.
73.3
73.3
N.A.
0
46.6
N.A.
N.A.
N.A.
0
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.8
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
42
0
9
17
34
0
0
0
0
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
34
17
9
0
0
0
17
% I
% Lys:
0
0
0
0
50
17
9
0
0
0
0
0
0
17
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
9
0
0
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
17
25
0
0
0
17
0
50
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
34
25
0
0
0
0
0
17
0
25
0
0
0
0
9
% T
% Val:
9
0
0
0
0
0
0
0
17
0
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _