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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCC2
All Species:
14.85
Human Site:
T889
Identified Species:
29.7
UniProt:
Q8IWJ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWJ2
NP_055450.1
1583
184657
T889
S
S
R
K
E
T
Q
T
V
K
E
E
L
E
S
Chimpanzee
Pan troglodytes
XP_001135112
1735
200938
E1078
D
P
L
S
S
V
K
E
L
E
E
K
I
E
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531770
1814
209228
T1120
S
S
K
K
E
A
Q
T
L
R
E
E
L
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHG3
1679
194426
T981
S
N
R
K
E
A
Q
T
L
R
E
E
L
E
S
Rat
Rattus norvegicus
NP_001101103
1679
195065
T981
S
N
R
K
E
A
Q
T
L
R
D
E
L
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513561
594
68554
Chicken
Gallus gallus
XP_425585
1693
196021
A999
T
S
R
K
E
M
Q
A
L
R
E
E
L
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097755
1135
130104
T498
A
Q
S
D
V
L
S
T
S
T
I
S
R
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34562
660
75020
K23
S
S
S
G
G
G
K
K
L
D
S
L
P
K
E
Sea Urchin
Strong. purpuratus
XP_794992
824
93860
Q187
M
E
C
T
Q
T
K
Q
L
K
E
E
L
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S2T0
788
89840
Y151
I
K
E
R
D
E
K
Y
A
D
L
D
A
K
F
Baker's Yeast
Sacchar. cerevisiae
P31111
875
100016
E238
S
C
L
E
T
L
Q
E
R
I
A
T
L
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
N.A.
72.4
N.A.
73.4
73
N.A.
32.2
57.8
N.A.
N.A.
N.A.
23.1
N.A.
20.9
22.7
Protein Similarity:
100
86.1
N.A.
79.6
N.A.
83.6
83.3
N.A.
34.5
74.1
N.A.
N.A.
N.A.
42.9
N.A.
31.6
36.9
P-Site Identity:
100
13.3
N.A.
66.6
N.A.
73.3
66.6
N.A.
0
60
N.A.
N.A.
N.A.
6.6
N.A.
13.3
33.3
P-Site Similarity:
100
53.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
80
N.A.
N.A.
N.A.
13.3
N.A.
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.8
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
25
0
9
9
0
9
0
9
9
0
% A
% Cys:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
9
0
0
0
0
17
9
9
0
9
0
% D
% Glu:
0
9
9
9
42
9
0
17
0
9
50
50
0
42
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
9
0
9
0
0
% I
% Lys:
0
9
9
42
0
0
34
9
0
17
0
9
0
17
0
% K
% Leu:
0
0
17
0
0
17
0
0
59
0
9
9
59
0
0
% L
% Met:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
9
0
0
9
0
50
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
34
9
0
0
0
0
9
34
0
0
9
0
0
% R
% Ser:
50
34
17
9
9
0
9
0
9
0
9
9
0
0
42
% S
% Thr:
9
0
0
9
9
17
0
42
0
9
0
9
0
9
0
% T
% Val:
0
0
0
0
9
9
0
0
9
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _