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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GCC2 All Species: 21.82
Human Site: Y379 Identified Species: 43.64
UniProt: Q8IWJ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWJ2 NP_055450.1 1583 184657 Y379 K Q E A I L N Y E S L R E I M
Chimpanzee Pan troglodytes XP_001135112 1735 200938 Y608 K Q E A I L N Y E S L R E I M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531770 1814 209228 Y610 K Q E A I L N Y E S L R E I M
Cat Felis silvestris
Mouse Mus musculus Q8CHG3 1679 194426 Y475 K Q E V V L N Y E S L R E M M
Rat Rattus norvegicus NP_001101103 1679 195065 Y475 K Q E V V L N Y E S L R E M M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513561 594 68554
Chicken Gallus gallus XP_425585 1693 196021 Y488 K E D A V L S Y D S L R E T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097755 1135 130104 K91 T E E V N N L K R K T K E D A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34562 660 75020
Sea Urchin Strong. purpuratus XP_794992 824 93860
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S2T0 788 89840
Baker's Yeast Sacchar. cerevisiae P31111 875 100016
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 N.A. 72.4 N.A. 73.4 73 N.A. 32.2 57.8 N.A. N.A. N.A. 23.1 N.A. 20.9 22.7
Protein Similarity: 100 86.1 N.A. 79.6 N.A. 83.6 83.3 N.A. 34.5 74.1 N.A. N.A. N.A. 42.9 N.A. 31.6 36.9
P-Site Identity: 100 100 N.A. 100 N.A. 80 80 N.A. 0 53.3 N.A. N.A. N.A. 13.3 N.A. 0 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 0 93.3 N.A. N.A. N.A. 26.6 N.A. 0 0
Percent
Protein Identity: N.A. N.A. N.A. 21.9 21.4 N.A.
Protein Similarity: N.A. N.A. N.A. 35.8 37 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 9 0 0 0 0 9 0 % D
% Glu: 0 17 50 0 0 0 0 0 42 0 0 0 59 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 25 0 0 0 0 0 0 0 0 25 0 % I
% Lys: 50 0 0 0 0 0 0 9 0 9 0 9 0 0 0 % K
% Leu: 0 0 0 0 0 50 9 0 0 0 50 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 42 % M
% Asn: 0 0 0 0 9 9 42 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 42 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 0 50 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 0 50 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % T
% Val: 0 0 0 25 25 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _