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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR125 All Species: 28.18
Human Site: T212 Identified Species: 77.5
UniProt: Q8IWK6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWK6 NP_660333.2 1321 146151 T212 K N I T V R D T R C V Y P K S
Chimpanzee Pan troglodytes XP_001164297 1320 146164 T211 K N I T V R D T R C V Y P K S
Rhesus Macaque Macaca mulatta XP_001104904 1319 146032 T210 R N I T V R D T R C V Y P K S
Dog Lupus familis XP_545977 1318 145233 T214 R N I T V R D T R C V Y P K S
Cat Felis silvestris
Mouse Mus musculus Q7TT36 1310 144705 T201 R N I T V R D T R C V Y P K S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513419 1289 142668 T182 R N I T V R E T R C A Y P K S
Chicken Gallus gallus XP_420763 1322 146745 T215 R N I T V R E T K C A Y P K S
Frog Xenopus laevis NP_001083670 1306 144699 T211 T A Q I S D K T M C A Y P S A
Zebra Danio Brachydanio rerio XP_001343104 1229 135194 P174 K I L E F D S P Y L L C D C N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.2 83.8 N.A. 92.6 N.A. N.A. 87.5 85.4 42.2 57.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 98.3 87.9 N.A. 95.3 N.A. N.A. 92.1 92.8 60.6 70 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 N.A. N.A. 80 73.3 26.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 93.3 33.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 0 34 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 89 0 12 0 12 0 % C
% Asp: 0 0 0 0 0 23 56 0 0 0 0 0 12 0 0 % D
% Glu: 0 0 0 12 0 0 23 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 78 12 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 34 0 0 0 0 0 12 0 12 0 0 0 0 78 0 % K
% Leu: 0 0 12 0 0 0 0 0 0 12 12 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 78 0 0 0 0 0 0 0 0 0 0 0 0 12 % N
% Pro: 0 0 0 0 0 0 0 12 0 0 0 0 89 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 56 0 0 0 0 78 0 0 67 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 12 0 12 0 0 0 0 0 0 12 78 % S
% Thr: 12 0 0 78 0 0 0 89 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 78 0 0 0 0 0 56 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 12 0 0 89 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _