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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC28A All Species: 10
Human Site: T149 Identified Species: 18.33
UniProt: Q8IWP9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWP9 NP_056254.1 274 30367 T149 K R V M K E K T K P Q G G E G
Chimpanzee Pan troglodytes XP_001171714 274 30359 T149 K R A M K E K T K P Q G G E G
Rhesus Macaque Macaca mulatta XP_001102480 200 21988 T83 P L Q H S F L T E V T D V Y E
Dog Lupus familis XP_533425 284 31813 T158 K R V M K E K T R P Q G G E G
Cat Felis silvestris
Mouse Mus musculus Q8CEG5 200 22045 T83 P L Q H S F L T E V T D V Y E
Rat Rattus norvegicus NP_001032878 184 20261 K67 K P P G G E G K G A Q A T P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508998 343 38222 P218 K R G I K E K P K P Q G G E G
Chicken Gallus gallus XP_419716 184 20284 K67 K P P G G E A K G A Q A A P I
Frog Xenopus laevis NP_001086253 189 21033 G72 S C E A G S P G P S L Q H S F
Zebra Danio Brachydanio rerio NP_956042 180 20156 K63 R P Q S Q S G K S N Q S S H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608652 316 35022 P195 K N P T A S M P N A S A H S D
Honey Bee Apis mellifera XP_001120401 227 25458 H110 E K E K Q K P H R P E L S K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001183635 229 24956 N112 H S K Q T T G N A P S R T S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 39.4 77.8 N.A. 39.4 62 N.A. 58.5 55.8 37.2 43.7 N.A. 25.9 27.3 N.A. 22.6
Protein Similarity: 100 98.9 52.5 82.3 N.A. 52.5 63.5 N.A. 65.3 60.9 48.5 54.7 N.A. 43.3 45.2 N.A. 41.2
P-Site Identity: 100 93.3 6.6 93.3 N.A. 6.6 20 N.A. 80 20 0 6.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 93.3 13.3 100 N.A. 13.3 20 N.A. 86.6 20 0 20 N.A. 6.6 53.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 0 8 0 8 24 0 24 8 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 8 % D
% Glu: 8 0 16 0 0 47 0 0 16 0 8 0 0 31 16 % E
% Phe: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 8 16 24 0 24 8 16 0 0 31 31 0 31 % G
% His: 8 0 0 16 0 0 0 8 0 0 0 0 16 8 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 31 % I
% Lys: 54 8 8 8 31 8 31 24 24 0 0 0 0 8 8 % K
% Leu: 0 16 0 0 0 0 16 0 0 0 8 8 0 0 0 % L
% Met: 0 0 0 24 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 8 8 0 0 0 0 0 % N
% Pro: 16 24 24 0 0 0 16 16 8 47 0 0 0 16 0 % P
% Gln: 0 0 24 8 16 0 0 0 0 0 54 8 0 0 0 % Q
% Arg: 8 31 0 0 0 0 0 0 16 0 0 8 0 0 0 % R
% Ser: 8 8 0 8 16 24 0 0 8 8 16 8 16 24 0 % S
% Thr: 0 0 0 8 8 8 0 39 0 0 16 0 16 0 0 % T
% Val: 0 0 16 0 0 0 0 0 0 16 0 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _