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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK2
All Species:
10.91
Human Site:
S418
Identified Species:
26.67
UniProt:
Q8IWQ3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWQ3
NP_003948.2
736
81633
S418
R
S
I
S
G
A
S
S
G
L
S
T
S
P
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850919
676
75195
S358
R
S
I
S
G
A
S
S
G
L
S
T
S
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z98
735
81715
S419
R
S
I
S
G
A
S
S
G
L
S
T
S
P
L
Rat
Rattus norvegicus
Q8VHF0
797
88733
V460
R
K
S
G
S
S
A
V
G
G
K
G
I
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA88
798
88848
L438
R
S
I
S
P
S
S
L
L
E
T
T
I
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
A727
P
P
P
P
G
G
G
A
G
L
M
Q
T
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
S534
P
G
G
N
S
S
G
S
T
S
A
S
P
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
G696
G
A
V
A
A
N
N
G
G
I
P
S
H
R
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
V199
K
L
Y
A
G
P
E
V
D
V
W
S
C
G
V
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
R591
S
Y
T
S
I
S
S
R
S
R
R
S
L
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
89.8
N.A.
97.9
25.4
N.A.
N.A.
27.4
N.A.
25.1
N.A.
50.9
N.A.
23.1
N.A.
Protein Similarity:
100
N.A.
N.A.
90.3
N.A.
98.7
43.2
N.A.
N.A.
43.9
N.A.
37.9
N.A.
63.5
N.A.
37.3
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
13.3
N.A.
N.A.
40
N.A.
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
26.6
N.A.
N.A.
53.3
N.A.
33.3
N.A.
40
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
33.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
20
10
30
10
10
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
10
50
10
20
10
60
10
0
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% H
% Ile:
0
0
40
0
10
0
0
0
0
10
0
0
20
0
0
% I
% Lys:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
10
10
40
0
0
10
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% N
% Pro:
20
10
10
10
10
10
0
0
0
0
10
0
10
30
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
50
0
0
0
0
0
0
10
0
10
10
0
0
20
0
% R
% Ser:
10
40
10
50
20
40
50
40
10
10
30
40
30
20
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
10
40
10
0
0
% T
% Val:
0
0
10
0
0
0
0
20
0
10
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _