KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK2
All Species:
5.76
Human Site:
Y717
Identified Species:
14.07
UniProt:
Q8IWQ3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWQ3
NP_003948.2
736
81633
Y717
G
P
G
G
D
A
E
Y
P
T
G
K
D
T
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850919
676
75195
R657
G
P
G
G
D
A
E
R
P
T
A
Q
D
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z98
735
81715
Y716
G
P
G
G
D
T
E
Y
P
M
G
K
D
M
A
Rat
Rattus norvegicus
Q8VHF0
797
88733
S768
V
C
K
L
P
R
L
S
L
N
G
V
R
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA88
798
88848
S763
T
T
F
S
Q
Q
Q
S
F
S
A
Q
S
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
E1108
D
D
A
Y
E
Q
V
E
P
M
S
G
M
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
S833
G
S
P
I
A
V
R
S
N
S
E
T
A
E
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
K1030
T
I
W
S
K
L
S
K
L
T
R
R
D
H
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
P494
D
I
Q
R
V
N
G
P
Q
F
L
F
L
D
L
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
E1316
G
G
G
K
I
K
E
E
H
T
K
L
D
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
89.8
N.A.
97.9
25.4
N.A.
N.A.
27.4
N.A.
25.1
N.A.
50.9
N.A.
23.1
N.A.
Protein Similarity:
100
N.A.
N.A.
90.3
N.A.
98.7
43.2
N.A.
N.A.
43.9
N.A.
37.9
N.A.
63.5
N.A.
37.3
N.A.
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
80
6.6
N.A.
N.A.
0
N.A.
6.6
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
80
6.6
N.A.
N.A.
26.6
N.A.
20
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
33.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
20
0
0
0
0
20
0
10
10
30
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
10
0
0
30
0
0
0
0
0
0
0
50
10
0
% D
% Glu:
0
0
0
0
10
0
40
20
0
0
10
0
0
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
10
10
0
10
0
10
0
% F
% Gly:
50
10
40
30
0
0
10
0
0
0
30
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% H
% Ile:
0
20
0
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
10
10
0
10
0
0
10
20
0
0
20
% K
% Leu:
0
0
0
10
0
10
10
0
20
0
10
10
10
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
20
0
0
10
10
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
10
0
0
0
10
10
% N
% Pro:
0
30
10
0
10
0
0
10
40
0
0
0
0
10
0
% P
% Gln:
0
0
10
0
10
20
10
0
10
0
0
20
0
0
0
% Q
% Arg:
0
0
0
10
0
10
10
10
0
0
10
10
10
0
0
% R
% Ser:
0
10
0
20
0
0
10
30
0
20
10
0
10
10
10
% S
% Thr:
20
10
0
0
0
10
0
0
0
40
0
10
0
10
0
% T
% Val:
10
0
0
0
10
10
10
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
20
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _