KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM59
All Species:
20.91
Human Site:
T144
Identified Species:
65.71
UniProt:
Q8IWR1
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWR1
NP_775107.1
403
47114
T144
A
Y
L
K
E
K
D
T
P
Q
K
L
L
E
Q
Chimpanzee
Pan troglodytes
XP_509783
407
46973
W152
L
F
Q
S
F
E
T
W
R
R
G
D
A
L
S
Rhesus Macaque
Macaca mulatta
XP_001093190
403
47343
T144
A
Y
F
K
E
K
D
T
P
Q
K
L
L
E
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q922Y2
403
47207
T144
A
Y
L
K
E
K
D
T
P
Q
K
L
L
K
Q
Rat
Rattus norvegicus
NP_001102415
403
47339
T144
A
Y
L
K
E
K
D
T
P
Q
K
L
F
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510595
403
46493
T144
A
Y
M
K
E
K
D
T
P
I
E
L
F
E
Q
Chicken
Gallus gallus
Q5ZMD4
408
46757
S144
A
Y
L
K
E
K
E
S
S
G
K
I
L
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001345555
344
39645
L115
Y
C
V
Q
D
R
K
L
I
C
G
F
C
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.9
94.5
N.A.
N.A.
82.6
83.8
N.A.
61.5
58
N.A.
38.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
52.8
96.7
N.A.
N.A.
90
91
N.A.
78.1
75
N.A.
58.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
N.A.
N.A.
93.3
86.6
N.A.
73.3
66.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
N.A.
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
13
0
0
13
0
0
% C
% Asp:
0
0
0
0
13
0
63
0
0
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
75
13
13
0
0
0
13
0
0
50
0
% E
% Phe:
0
13
13
0
13
0
0
0
0
0
0
13
25
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
13
25
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
13
0
13
0
0
0
% I
% Lys:
0
0
0
75
0
75
13
0
0
0
63
0
0
25
0
% K
% Leu:
13
0
50
0
0
0
0
13
0
0
0
63
50
25
0
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
63
0
0
0
0
0
0
% P
% Gln:
0
0
13
13
0
0
0
0
0
50
0
0
0
0
75
% Q
% Arg:
0
0
0
0
0
13
0
0
13
13
0
0
0
0
0
% R
% Ser:
0
0
0
13
0
0
0
13
13
0
0
0
0
0
13
% S
% Thr:
0
0
0
0
0
0
13
63
0
0
0
0
0
0
13
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
13
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _