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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LMTK2
All Species:
15.76
Human Site:
S525
Identified Species:
38.52
UniProt:
Q8IWU2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWU2
NP_055731.2
1503
164900
S525
G
P
G
K
Q
D
D
S
G
Q
D
V
P
L
R
Chimpanzee
Pan troglodytes
XP_001134909
1503
164940
S525
G
P
G
K
Q
D
D
S
G
Q
D
V
P
L
R
Rhesus Macaque
Macaca mulatta
XP_001111343
1394
145722
G443
R
P
G
G
G
G
V
G
P
G
P
G
A
A
G
Dog
Lupus familis
XP_851196
1606
175541
S518
G
P
G
K
Q
D
D
S
G
Q
D
V
P
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYD6
1471
160455
V508
S
M
F
F
P
V
E
V
F
E
N
S
L
S
D
Rat
Rattus norvegicus
NP_001131113
1531
165309
L522
L
E
Y
P
P
A
L
L
T
T
E
V
D
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512369
1956
215331
S500
G
P
G
K
Q
D
E
S
G
Q
Q
V
P
L
K
Chicken
Gallus gallus
XP_001232429
1461
163074
S495
G
P
G
A
Q
D
G
S
G
Q
E
A
S
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693087
1445
159087
N484
H
D
H
Y
D
S
H
N
R
S
A
M
D
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624443
1396
159523
W445
C
L
D
F
E
Q
R
W
E
N
L
R
V
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
31
78
N.A.
76.1
72.6
N.A.
47
54.8
N.A.
44.1
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
100
99.7
46.1
83.6
N.A.
83.9
80.4
N.A.
56.4
68.5
N.A.
59.6
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
100
100
13.3
86.6
N.A.
0
6.6
N.A.
80
60
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
13.3
86.6
N.A.
20
13.3
N.A.
93.3
66.6
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
0
10
10
10
10
20
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
10
50
30
0
0
0
30
0
20
0
10
% D
% Glu:
0
10
0
0
10
0
20
0
10
10
20
0
0
0
0
% E
% Phe:
0
0
10
20
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
50
0
60
10
10
10
10
10
50
10
0
10
0
0
20
% G
% His:
10
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
10
0
0
0
0
10
10
0
0
10
0
10
40
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
10
0
0
20
0
% N
% Pro:
0
60
0
10
20
0
0
0
10
0
10
0
40
0
10
% P
% Gln:
0
0
0
0
50
10
0
0
0
50
10
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
10
0
10
0
0
10
0
10
20
% R
% Ser:
10
0
0
0
0
10
0
50
0
10
0
10
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
10
% T
% Val:
0
0
0
0
0
10
10
10
0
0
0
50
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _