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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SULF2 All Species: 16.97
Human Site: S860 Identified Species: 33.94
UniProt: Q8IWU5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWU5 NP_001155313.1 870 100455 S860 M K R P S S K S L G Q L W E G
Chimpanzee Pan troglodytes XP_514701 348 40666 Q341 P S S K S L G Q L W E G W E G
Rhesus Macaque Macaca mulatta XP_001106412 1204 136421 S1194 M K R P S S K S L G Q L W E G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8CFG0 875 100451 S865 M K R P S S K S L G Q L W E G
Rat Rattus norvegicus Q8VI60 870 100841 H860 E G G N Y D P H R G Q L W D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510791 860 97763 L852 Q L D T H E P L L L K L V T F
Chicken Gallus gallus XP_417386 877 102190 S867 K R P S S S K S L G Q L W E G
Frog Xenopus laevis NP_001088414 872 101568 L863 K R P S S K S L G Q L W D G W
Zebra Danio Brachydanio rerio NP_001003833 885 102377 S875 V R K P V S K S L G Q I W E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEX0 1114 127285 G1051 S P L A G A V G N Y A F V G P
Honey Bee Apis mellifera XP_393715 1436 166412 I1388 F V P S T L Q I I R E S E L S
Nematode Worm Caenorhab. elegans Q21376 709 83765 L702 R V N E K S F L T Y Q P E K T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 71.5 N.A. N.A. 93.9 65.6 N.A. 56.4 86 81.7 74.1 N.A. 34.8 30 38.6 N.A.
Protein Similarity: 100 37.5 71.8 N.A. N.A. 96 79.6 N.A. 69.8 92.5 90.8 84.8 N.A. 50.9 42.4 55.6 N.A.
P-Site Identity: 100 33.3 100 N.A. N.A. 100 33.3 N.A. 13.3 73.3 6.6 66.6 N.A. 0 0 13.3 N.A.
P-Site Similarity: 100 40 100 N.A. N.A. 100 40 N.A. 20 80 13.3 93.3 N.A. 6.6 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 9 0 0 0 0 0 0 9 9 0 % D
% Glu: 9 0 0 9 0 9 0 0 0 0 17 0 17 50 0 % E
% Phe: 9 0 0 0 0 0 9 0 0 0 0 9 0 0 9 % F
% Gly: 0 9 9 0 9 0 9 9 9 50 0 9 0 17 59 % G
% His: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 9 0 0 9 0 0 0 % I
% Lys: 17 25 9 9 9 9 42 0 0 0 9 0 0 9 0 % K
% Leu: 0 9 9 0 0 17 0 25 59 9 9 50 0 9 0 % L
% Met: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 9 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 9 9 25 34 0 0 17 0 0 0 0 9 0 0 9 % P
% Gln: 9 0 0 0 0 0 9 9 0 9 59 0 0 0 0 % Q
% Arg: 9 25 25 0 0 0 0 0 9 9 0 0 0 0 0 % R
% Ser: 9 9 9 25 50 50 9 42 0 0 0 9 0 0 9 % S
% Thr: 0 0 0 9 9 0 0 0 9 0 0 0 0 9 9 % T
% Val: 9 17 0 0 9 0 9 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 9 59 0 9 % W
% Tyr: 0 0 0 0 9 0 0 0 0 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _