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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SULF2 All Species: 36.36
Human Site: Y152 Identified Species: 72.73
UniProt: Q8IWU5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWU5 NP_001155313.1 870 100455 Y152 L N E Y N G S Y V P P G W K E
Chimpanzee Pan troglodytes XP_514701 348 40666
Rhesus Macaque Macaca mulatta XP_001106412 1204 136421 Y486 L N E Y N G S Y V P P G W K E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8CFG0 875 100451 Y152 L N E Y N G S Y V P P G W K E
Rat Rattus norvegicus Q8VI60 870 100841 Y151 L N E Y N G S Y I P P G W R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510791 860 97763 C191 V Y T N N E N C S S P S W Q A
Chicken Gallus gallus XP_417386 877 102190 Y152 L N E Y N G S Y V P P G W K E
Frog Xenopus laevis NP_001088414 872 101568 Y151 L N E Y N G T Y V P P G W K E
Zebra Danio Brachydanio rerio NP_001003833 885 102377 Y154 L N E Y N G T Y I P P G W R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEX0 1114 127285 Y162 L N K Y N G S Y I P P G W R E
Honey Bee Apis mellifera XP_393715 1436 166412 Y183 L N K Y N G S Y I P P G W R E
Nematode Worm Caenorhab. elegans Q21376 709 83765 G72 R G T E F T S G Y V T T P I C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 71.5 N.A. N.A. 93.9 65.6 N.A. 56.4 86 81.7 74.1 N.A. 34.8 30 38.6 N.A.
Protein Similarity: 100 37.5 71.8 N.A. N.A. 96 79.6 N.A. 69.8 92.5 90.8 84.8 N.A. 50.9 42.4 55.6 N.A.
P-Site Identity: 100 0 100 N.A. N.A. 100 86.6 N.A. 20 100 93.3 80 N.A. 80 80 6.6 N.A.
P-Site Similarity: 100 0 100 N.A. N.A. 100 100 N.A. 40 100 100 100 N.A. 100 100 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 59 9 0 9 0 0 0 0 0 0 0 0 75 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 75 0 9 0 0 0 75 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 34 0 0 0 0 9 0 % I
% Lys: 0 0 17 0 0 0 0 0 0 0 0 0 0 42 0 % K
% Leu: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 75 0 9 84 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 75 84 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % R
% Ser: 0 0 0 0 0 0 67 0 9 9 0 9 0 0 0 % S
% Thr: 0 0 17 0 0 9 17 0 0 0 9 9 0 0 0 % T
% Val: 9 0 0 0 0 0 0 0 42 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 84 0 0 % W
% Tyr: 0 9 0 75 0 0 0 75 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _