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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SULF1 All Species: 7.58
Human Site: Y493 Identified Species: 23.81
UniProt: Q8IWU6 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWU6 NP_001121676.1 871 101027 Y493 R Q S T R N L Y A R G F H D K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106412 1204 136421 P828 G A L S N L V P K Y Y G Q G S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8K007 870 100904 Y493 R Q N A R N L Y S R G L H D K
Rat Rattus norvegicus Q8VI60 870 100841 Y493 R Q N A R N L Y S R G L Q D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510791 860 97763 R487 N K K T K I W R D T F L V E R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEX0 1114 127285 P621 V Y T K I R A P S A G L H R V
Honey Bee Apis mellifera XP_393715 1436 166412 L803 F P P K C S V L P Q G G V N C
Nematode Worm Caenorhab. elegans Q21376 709 83765 A393 K K K K H M T A L K P W R D T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 49.6 N.A. N.A. 93 93.3 N.A. 67.5 N.A. N.A. N.A. N.A. 34.6 30.8 38.5 N.A.
Protein Similarity: 100 N.A. 59.3 N.A. N.A. 96.3 96.2 N.A. 75.6 N.A. N.A. N.A. N.A. 49.9 43.1 54.3 N.A.
P-Site Identity: 100 N.A. 0 N.A. N.A. 73.3 66.6 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3 6.6 6.6 N.A.
P-Site Similarity: 100 N.A. 13.3 N.A. N.A. 86.6 80 N.A. 33.3 N.A. N.A. N.A. N.A. 26.6 33.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 25 0 0 13 13 13 13 0 0 0 0 0 % A
% Cys: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 0 0 0 0 0 0 0 0 13 0 0 0 0 50 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % E
% Phe: 13 0 0 0 0 0 0 0 0 0 13 13 0 0 0 % F
% Gly: 13 0 0 0 0 0 0 0 0 0 63 25 0 13 0 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 0 38 0 0 % H
% Ile: 0 0 0 0 13 13 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 25 25 38 13 0 0 0 13 13 0 0 0 0 38 % K
% Leu: 0 0 13 0 0 13 38 13 13 0 0 50 0 0 0 % L
% Met: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 25 0 13 38 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 13 13 0 0 0 0 25 13 0 13 0 0 0 0 % P
% Gln: 0 38 0 0 0 0 0 0 0 13 0 0 25 0 0 % Q
% Arg: 38 0 0 0 38 13 0 13 0 38 0 0 13 13 13 % R
% Ser: 0 0 13 13 0 13 0 0 38 0 0 0 0 0 13 % S
% Thr: 0 0 13 25 0 0 13 0 0 13 0 0 0 0 13 % T
% Val: 13 0 0 0 0 0 25 0 0 0 0 0 25 0 13 % V
% Trp: 0 0 0 0 0 0 13 0 0 0 0 13 0 0 0 % W
% Tyr: 0 13 0 0 0 0 0 38 0 13 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _