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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBR1 All Species: 21.21
Human Site: S346 Identified Species: 38.89
UniProt: Q8IWV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWV7 NP_777576.1 1749 200211 S346 C L R E E P D S E N P C L I S
Chimpanzee Pan troglodytes XP_510341 1957 222467 S536 C L R E E P D S E N P C L I S
Rhesus Macaque Macaca mulatta XP_001105721 1725 197380 M356 L I F S S F F M E M E Y K K L
Dog Lupus familis XP_544645 1753 200457 S346 C L R E E P G S E N P C L I S
Cat Felis silvestris
Mouse Mus musculus O70481 1757 200198 S346 C L V E E P G S E N P C L I S
Rat Rattus norvegicus XP_001080919 1747 198866 S346 C L I E E P G S E H P C L I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509245 1754 200216 G346 G L Q E G P D G E N S Y L V D
Chicken Gallus gallus XP_421165 1823 207995 S415 C L K E E A G S E K P C F I S
Frog Xenopus laevis NP_001089665 1750 198678 G346 G L Q E G P E G E N S S L V D
Zebra Danio Brachydanio rerio XP_001922263 1073 120679
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX91 1824 208342 K361 F S E L V Q R K Q E T F C I R
Honey Bee Apis mellifera XP_394362 1779 202529 L366 N V A L N T K L P V I S I V E
Nematode Worm Caenorhab. elegans P91133 1927 218080 S360 S P G P S R D S S T F T M L E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.3 96.6 95.6 N.A. 92.1 90.5 N.A. 48 75 46.7 35.8 N.A. 31.6 36 24.2 N.A.
Protein Similarity: 100 88.7 97.7 98.1 N.A. 95.7 94.9 N.A. 67.1 85.4 65.8 46.2 N.A. 49.1 55.5 43.1 N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 86.6 80 N.A. 46.6 66.6 40 0 N.A. 6.6 0 13.3 N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 86.6 86.6 N.A. 60 73.3 60 0 N.A. 13.3 20 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % A
% Cys: 47 0 0 0 0 0 0 0 0 0 0 47 8 0 0 % C
% Asp: 0 0 0 0 0 0 31 0 0 0 0 0 0 0 16 % D
% Glu: 0 0 8 62 47 0 8 0 70 8 8 0 0 0 16 % E
% Phe: 8 0 8 0 0 8 8 0 0 0 8 8 8 0 0 % F
% Gly: 16 0 8 0 16 0 31 16 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 8 0 8 54 0 % I
% Lys: 0 0 8 0 0 0 8 8 0 8 0 0 8 8 0 % K
% Leu: 8 62 0 16 0 0 0 8 0 0 0 0 54 8 8 % L
% Met: 0 0 0 0 0 0 0 8 0 8 0 0 8 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 0 47 0 0 0 0 0 % N
% Pro: 0 8 0 8 0 54 0 0 8 0 47 0 0 0 0 % P
% Gln: 0 0 16 0 0 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 24 0 0 8 8 0 0 0 0 0 0 0 8 % R
% Ser: 8 8 0 8 16 0 0 54 8 0 16 16 0 0 47 % S
% Thr: 0 0 0 0 0 8 0 0 0 8 8 8 0 0 0 % T
% Val: 0 8 8 0 8 0 0 0 0 8 0 0 0 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _