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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBR1
All Species:
21.21
Human Site:
S346
Identified Species:
38.89
UniProt:
Q8IWV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWV7
NP_777576.1
1749
200211
S346
C
L
R
E
E
P
D
S
E
N
P
C
L
I
S
Chimpanzee
Pan troglodytes
XP_510341
1957
222467
S536
C
L
R
E
E
P
D
S
E
N
P
C
L
I
S
Rhesus Macaque
Macaca mulatta
XP_001105721
1725
197380
M356
L
I
F
S
S
F
F
M
E
M
E
Y
K
K
L
Dog
Lupus familis
XP_544645
1753
200457
S346
C
L
R
E
E
P
G
S
E
N
P
C
L
I
S
Cat
Felis silvestris
Mouse
Mus musculus
O70481
1757
200198
S346
C
L
V
E
E
P
G
S
E
N
P
C
L
I
S
Rat
Rattus norvegicus
XP_001080919
1747
198866
S346
C
L
I
E
E
P
G
S
E
H
P
C
L
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509245
1754
200216
G346
G
L
Q
E
G
P
D
G
E
N
S
Y
L
V
D
Chicken
Gallus gallus
XP_421165
1823
207995
S415
C
L
K
E
E
A
G
S
E
K
P
C
F
I
S
Frog
Xenopus laevis
NP_001089665
1750
198678
G346
G
L
Q
E
G
P
E
G
E
N
S
S
L
V
D
Zebra Danio
Brachydanio rerio
XP_001922263
1073
120679
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX91
1824
208342
K361
F
S
E
L
V
Q
R
K
Q
E
T
F
C
I
R
Honey Bee
Apis mellifera
XP_394362
1779
202529
L366
N
V
A
L
N
T
K
L
P
V
I
S
I
V
E
Nematode Worm
Caenorhab. elegans
P91133
1927
218080
S360
S
P
G
P
S
R
D
S
S
T
F
T
M
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
96.6
95.6
N.A.
92.1
90.5
N.A.
48
75
46.7
35.8
N.A.
31.6
36
24.2
N.A.
Protein Similarity:
100
88.7
97.7
98.1
N.A.
95.7
94.9
N.A.
67.1
85.4
65.8
46.2
N.A.
49.1
55.5
43.1
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
80
N.A.
46.6
66.6
40
0
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
86.6
N.A.
60
73.3
60
0
N.A.
13.3
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
47
0
0
0
0
0
0
0
0
0
0
47
8
0
0
% C
% Asp:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
16
% D
% Glu:
0
0
8
62
47
0
8
0
70
8
8
0
0
0
16
% E
% Phe:
8
0
8
0
0
8
8
0
0
0
8
8
8
0
0
% F
% Gly:
16
0
8
0
16
0
31
16
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
8
0
8
54
0
% I
% Lys:
0
0
8
0
0
0
8
8
0
8
0
0
8
8
0
% K
% Leu:
8
62
0
16
0
0
0
8
0
0
0
0
54
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
47
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
54
0
0
8
0
47
0
0
0
0
% P
% Gln:
0
0
16
0
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
24
0
0
8
8
0
0
0
0
0
0
0
8
% R
% Ser:
8
8
0
8
16
0
0
54
8
0
16
16
0
0
47
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
8
8
0
0
0
% T
% Val:
0
8
8
0
8
0
0
0
0
8
0
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _