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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBR2 All Species: 31.52
Human Site: S1133 Identified Species: 57.78
UniProt: Q8IWV8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWV8 NP_056070.1 1755 200538 S1133 L A A F V Q R S T V L S K N R
Chimpanzee Pan troglodytes XP_001134707 900 102099 R341 Q R R Q Q R L R L H T S Y D V
Rhesus Macaque Macaca mulatta XP_001088394 1755 200302 S1133 L A A F V Q R S T V L S K N R
Dog Lupus familis XP_532138 1755 200518 S1133 L A A F V Q R S T V L S K N R
Cat Felis silvestris
Mouse Mus musculus Q6WKZ8 1755 199137 S1133 L A A F V Q R S T V L S K D R
Rat Rattus norvegicus XP_001061882 1755 198999 S1133 L A A F V Q R S T V L S K D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509245 1754 200216 S1133 L A A F V Q R S T V L S K N R
Chicken Gallus gallus XP_419446 1732 198074 S1114 L A A F I Q R S T V L S K N R
Frog Xenopus laevis NP_001089665 1750 198678 S1135 L A A F I Q R S T V F S K N R
Zebra Danio Brachydanio rerio XP_001921622 1014 115965 L455 D H L R H R D L Q G R F Q F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX91 1824 208342 R1139 F E N C A I S R G G R Q L V S
Honey Bee Apis mellifera XP_394362 1779 202529 F1129 P A M V L A A F V Q Q S T V L
Nematode Worm Caenorhab. elegans P91133 1927 218080 Q1165 V C A A F I Q Q S Q L F T H K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.9 96.6 96.1 N.A. 90.5 90.6 N.A. 89.8 88.3 80.2 45.1 N.A. 33.4 40.9 25.4 N.A.
Protein Similarity: 100 51.1 97.7 98.1 N.A. 95.3 95.4 N.A. 95 93.7 89.9 51.7 N.A. 51.4 59.9 44.3 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 100 93.3 86.6 0 N.A. 0 13.3 13.3 N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 100 93.3 13.3 N.A. 0 20 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 70 8 8 8 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 0 0 0 0 0 24 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 8 0 0 62 8 0 0 8 0 0 8 16 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 16 0 0 0 0 0 % G
% His: 0 8 0 0 8 0 0 0 0 8 0 0 0 8 0 % H
% Ile: 0 0 0 0 16 16 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 62 0 8 % K
% Leu: 62 0 8 0 8 0 8 8 8 0 62 0 8 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 47 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 8 8 62 8 8 8 16 8 8 8 0 0 % Q
% Arg: 0 8 8 8 0 16 62 16 0 0 16 0 0 0 62 % R
% Ser: 0 0 0 0 0 0 8 62 8 0 0 77 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 62 0 8 0 16 0 0 % T
% Val: 8 0 0 8 47 0 0 0 8 62 0 0 0 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _