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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADHFE1
All Species:
4.55
Human Site:
S165
Identified Species:
7.69
UniProt:
Q8IWW8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWW8
NP_653251.2
467
50308
S165
S
D
F
L
D
Y
V
S
A
P
I
G
K
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094680
467
50184
S165
S
D
F
L
D
Y
V
S
A
P
I
G
K
G
K
Dog
Lupus familis
XP_849448
419
45266
L130
G
K
P
V
S
V
P
L
K
P
L
I
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0N6
465
49919
N163
S
E
F
L
D
Y
V
N
A
P
I
G
K
G
K
Rat
Rattus norvegicus
Q4QQW3
467
50207
N165
S
E
F
L
D
Y
V
N
A
P
I
G
K
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511833
542
59240
N240
S
D
F
L
D
Y
V
N
A
P
I
G
K
G
K
Chicken
Gallus gallus
XP_424090
419
45207
L130
G
K
A
V
T
V
P
L
K
P
L
I
A
V
P
Frog
Xenopus laevis
Q08B39
463
50154
N161
S
D
F
L
D
Y
V
N
P
P
I
G
K
G
K
Zebra Danio
Brachydanio rerio
NP_996969
471
50630
N169
A
E
F
L
D
F
V
N
A
P
I
G
K
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W265
464
49999
N162
A
E
F
L
D
Y
V
N
C
P
I
G
R
G
K
Honey Bee
Apis mellifera
XP_624450
418
45967
Q129
K
E
K
P
I
T
I
Q
L
K
P
L
V
A
V
Nematode Worm
Caenorhab. elegans
Q9U2M4
465
50487
G162
A
D
F
L
D
F
V
G
P
P
F
G
K
S
M
Sea Urchin
Strong. purpuratus
XP_780928
479
51618
N177
A
D
F
L
D
F
V
N
A
P
V
G
K
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10127
382
41124
V93
K
E
Q
N
S
E
I
V
V
S
I
G
G
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
83.3
N.A.
89.2
89.7
N.A.
74.7
75.1
79.2
71.5
N.A.
58.4
55.4
47.5
62.2
Protein Similarity:
100
N.A.
98.2
85.8
N.A.
94
94.2
N.A.
81.9
83.3
88.8
84.2
N.A.
75.5
69.5
63.1
76.8
P-Site Identity:
100
N.A.
100
6.6
N.A.
86.6
86.6
N.A.
93.3
6.6
86.6
73.3
N.A.
66.6
0
53.3
66.6
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
100
20
93.3
100
N.A.
93.3
13.3
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
8
0
0
0
0
0
50
0
0
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
43
0
0
72
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
43
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
72
0
0
22
0
0
0
0
8
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
8
0
0
0
79
8
72
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
15
0
0
0
65
15
0
0
0
% I
% Lys:
15
15
8
0
0
0
0
0
15
8
0
0
65
0
58
% K
% Leu:
0
0
0
72
0
0
0
15
8
0
15
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
0
0
50
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
15
0
15
86
8
0
0
0
15
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
43
0
0
0
15
0
0
15
0
8
0
0
0
8
8
% S
% Thr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
15
0
15
72
8
8
0
8
0
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _