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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADHFE1
All Species:
11.82
Human Site:
S37
Identified Species:
20
UniProt:
Q8IWW8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWW8
NP_653251.2
467
50308
S37
Y
S
Q
A
P
G
L
S
P
S
G
K
T
T
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094680
467
50184
S37
Y
S
Q
A
P
G
L
S
P
S
G
K
T
T
D
Dog
Lupus familis
XP_849448
419
45266
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0N6
465
49919
G35
H
T
Y
S
Q
A
P
G
P
S
G
K
T
A
D
Rat
Rattus norvegicus
Q4QQW3
467
50207
S37
Y
S
Q
V
P
G
L
S
P
S
G
K
T
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511833
542
59240
S112
S
Q
A
P
E
I
A
S
S
I
G
R
T
T
D
Chicken
Gallus gallus
XP_424090
419
45207
Frog
Xenopus laevis
Q08B39
463
50154
A36
Y
S
Q
A
P
A
T
A
R
T
T
D
Y
A
F
Zebra Danio
Brachydanio rerio
NP_996969
471
50630
H41
R
A
S
A
G
E
A
H
V
C
D
R
K
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W265
464
49999
A34
Y
G
S
A
A
P
T
A
S
Q
T
G
R
M
E
Honey Bee
Apis mellifera
XP_624450
418
45967
Nematode Worm
Caenorhab. elegans
Q9U2M4
465
50487
H34
P
F
K
L
A
K
L
H
G
N
N
K
S
T
D
Sea Urchin
Strong. purpuratus
XP_780928
479
51618
S49
R
M
P
L
K
S
C
S
T
S
A
E
Q
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10127
382
41124
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
83.3
N.A.
89.2
89.7
N.A.
74.7
75.1
79.2
71.5
N.A.
58.4
55.4
47.5
62.2
Protein Similarity:
100
N.A.
98.2
85.8
N.A.
94
94.2
N.A.
81.9
83.3
88.8
84.2
N.A.
75.5
69.5
63.1
76.8
P-Site Identity:
100
N.A.
100
0
N.A.
40
93.3
N.A.
33.3
0
33.3
20
N.A.
13.3
0
26.6
20
P-Site Similarity:
100
N.A.
100
0
N.A.
60
93.3
N.A.
40
0
46.6
33.3
N.A.
26.6
0
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
36
15
15
15
15
0
0
8
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
58
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
8
22
0
8
8
0
36
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
8
0
0
0
0
0
36
8
0
0
% K
% Leu:
0
0
0
15
0
0
29
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
8
0
8
8
29
8
8
0
29
0
0
0
0
8
0
% P
% Gln:
0
8
29
0
8
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
15
0
0
0
0
0
0
0
8
0
0
15
8
0
0
% R
% Ser:
8
29
15
8
0
8
0
36
15
36
0
0
8
0
0
% S
% Thr:
0
8
0
0
0
0
15
0
8
8
15
0
36
43
0
% T
% Val:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
36
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _