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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADHFE1
All Species:
25.45
Human Site:
S85
Identified Species:
43.08
UniProt:
Q8IWW8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWW8
NP_653251.2
467
50308
S85
L
M
T
D
K
N
L
S
K
L
P
P
V
Q
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094680
467
50184
S85
L
M
T
D
K
N
L
S
Q
L
P
P
V
Q
V
Dog
Lupus familis
XP_849448
419
45266
K51
M
V
M
D
S
L
V
K
N
G
I
N
F
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0N6
465
49919
S83
L
M
T
D
K
N
L
S
Q
L
P
P
V
Q
I
Rat
Rattus norvegicus
Q4QQW3
467
50207
S85
L
M
T
D
K
N
L
S
Q
L
P
P
V
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511833
542
59240
S160
V
M
T
D
E
N
L
S
Q
L
P
P
V
E
T
Chicken
Gallus gallus
XP_424090
419
45207
K51
A
V
L
N
S
L
T
K
S
G
I
N
F
Q
M
Frog
Xenopus laevis
Q08B39
463
50154
S81
V
M
T
D
R
N
L
S
E
L
S
P
V
K
A
Zebra Danio
Brachydanio rerio
NP_996969
471
50630
S89
L
M
T
D
R
T
L
S
Q
L
P
P
V
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W265
464
49999
V82
L
V
T
D
K
N
V
V
Q
L
P
S
V
K
V
Honey Bee
Apis mellifera
XP_624450
418
45967
I50
K
T
A
I
N
S
L
I
K
Y
K
N
Q
T
T
Nematode Worm
Caenorhab. elegans
Q9U2M4
465
50487
Q82
L
I
T
D
K
N
V
Q
N
T
I
A
F
K
N
Sea Urchin
Strong. purpuratus
XP_780928
479
51618
A97
V
V
T
D
K
K
L
A
S
L
P
I
M
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10127
382
41124
F14
F
Y
I
P
P
I
S
F
F
G
E
G
A
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
83.3
N.A.
89.2
89.7
N.A.
74.7
75.1
79.2
71.5
N.A.
58.4
55.4
47.5
62.2
Protein Similarity:
100
N.A.
98.2
85.8
N.A.
94
94.2
N.A.
81.9
83.3
88.8
84.2
N.A.
75.5
69.5
63.1
76.8
P-Site Identity:
100
N.A.
93.3
13.3
N.A.
86.6
86.6
N.A.
66.6
6.6
60
66.6
N.A.
60
13.3
33.3
40
P-Site Similarity:
100
N.A.
100
40
N.A.
100
100
N.A.
93.3
26.6
86.6
80
N.A.
86.6
20
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
0
0
0
8
8
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
79
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
8
0
0
8
8
% E
% Phe:
8
0
0
0
0
0
0
8
8
0
0
0
22
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
22
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
8
0
8
0
0
22
8
0
0
15
% I
% Lys:
8
0
0
0
50
8
0
15
15
0
8
0
0
29
0
% K
% Leu:
50
0
8
0
0
15
65
0
0
65
0
0
0
8
0
% L
% Met:
8
50
8
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
8
8
58
0
0
15
0
0
22
0
0
8
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
58
50
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
43
0
0
0
8
36
0
% Q
% Arg:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
15
8
8
50
15
0
8
8
0
0
0
% S
% Thr:
0
8
72
0
0
8
8
0
0
8
0
0
0
8
22
% T
% Val:
22
29
0
0
0
0
22
8
0
0
0
0
58
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _