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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADHFE1
All Species:
34.24
Human Site:
T372
Identified Species:
57.95
UniProt:
Q8IWW8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWW8
NP_653251.2
467
50308
T372
S
P
A
V
F
T
F
T
A
Q
M
F
P
E
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094680
467
50184
T372
S
P
A
V
F
T
F
T
A
Q
M
F
P
E
R
Dog
Lupus familis
XP_849448
419
45266
L333
Q
M
S
P
E
R
H
L
E
T
A
E
I
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0N6
465
49919
T370
S
P
A
V
F
T
F
T
A
Q
M
F
P
E
R
Rat
Rattus norvegicus
Q4QQW3
467
50207
T372
S
P
A
V
F
T
F
T
A
Q
M
F
P
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511833
542
59240
T447
S
P
A
V
F
T
F
T
A
Q
M
Y
P
E
R
Chicken
Gallus gallus
XP_424090
419
45207
L333
Q
V
H
P
E
R
H
L
E
A
A
E
I
L
G
Frog
Xenopus laevis
Q08B39
463
50154
T368
S
P
A
V
F
S
F
T
G
L
M
C
P
E
R
Zebra Danio
Brachydanio rerio
NP_996969
471
50630
T376
S
P
A
V
F
E
F
T
A
N
M
C
P
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W265
464
49999
T369
A
P
A
V
F
E
F
T
A
P
A
C
P
D
R
Honey Bee
Apis mellifera
XP_624450
418
45967
L332
S
A
C
P
E
K
H
L
E
A
A
E
L
L
G
Nematode Worm
Caenorhab. elegans
Q9U2M4
465
50487
T369
A
V
A
D
F
E
F
T
T
A
A
C
P
D
R
Sea Urchin
Strong. purpuratus
XP_780928
479
51618
T384
A
P
A
V
F
N
F
T
G
P
S
C
P
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10127
382
41124
C296
V
Q
E
A
N
M
Q
C
P
K
A
K
K
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
83.3
N.A.
89.2
89.7
N.A.
74.7
75.1
79.2
71.5
N.A.
58.4
55.4
47.5
62.2
Protein Similarity:
100
N.A.
98.2
85.8
N.A.
94
94.2
N.A.
81.9
83.3
88.8
84.2
N.A.
75.5
69.5
63.1
76.8
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
93.3
0
73.3
80
N.A.
60
6.6
40
60
P-Site Similarity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
100
0
80
80
N.A.
73.3
6.6
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
72
8
0
0
0
0
50
22
43
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
36
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
15
0
% D
% Glu:
0
0
8
0
22
22
0
0
22
0
0
22
0
58
0
% E
% Phe:
0
0
0
0
72
0
72
0
0
0
0
29
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
22
% G
% His:
0
0
8
0
0
0
22
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
22
0
8
0
0
8
22
8
% L
% Met:
0
8
0
0
0
8
0
0
0
0
50
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
65
0
22
0
0
0
0
8
15
0
0
72
0
0
% P
% Gln:
15
8
0
0
0
0
8
0
0
36
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
0
0
0
0
0
0
0
8
72
% R
% Ser:
58
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
36
0
72
8
8
0
0
0
0
0
% T
% Val:
8
15
0
65
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _