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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADHFE1
All Species:
22.12
Human Site:
T393
Identified Species:
37.44
UniProt:
Q8IWW8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWW8
NP_653251.2
467
50308
T393
I
L
G
A
D
T
R
T
A
R
I
Q
D
A
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094680
467
50184
T393
I
L
G
A
D
T
R
T
T
R
I
Q
D
A
G
Dog
Lupus familis
XP_849448
419
45266
D350
T
R
T
A
R
I
P
D
A
G
P
I
L
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0N6
465
49919
T391
I
L
G
A
N
I
R
T
A
R
I
Q
D
A
G
Rat
Rattus norvegicus
Q4QQW3
467
50207
T393
I
L
G
A
N
I
R
T
A
K
I
Q
D
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511833
542
59240
T468
I
L
G
A
D
I
R
T
A
R
I
K
D
A
G
Chicken
Gallus gallus
XP_424090
419
45207
D350
I
R
T
A
R
I
K
D
A
G
L
I
L
A
D
Frog
Xenopus laevis
Q08B39
463
50154
T389
I
L
G
A
D
L
R
T
A
K
I
K
D
A
G
Zebra Danio
Brachydanio rerio
NP_996969
471
50630
N397
I
L
G
T
D
V
S
N
V
K
K
D
D
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W265
464
49999
G390
L
L
G
A
E
V
R
G
V
E
K
A
D
A
G
Honey Bee
Apis mellifera
XP_624450
418
45967
D349
I
S
Q
A
K
K
S
D
A
G
K
I
L
G
D
Nematode Worm
Caenorhab. elegans
Q9U2M4
465
50487
N391
L
G
A
D
I
P
N
N
A
S
N
E
Y
I
S
Sea Urchin
Strong. purpuratus
XP_780928
479
51618
G405
L
L
G
T
D
I
T
G
V
K
L
A
D
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10127
382
41124
S313
I
A
L
H
F
G
A
S
Q
E
D
P
E
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
83.3
N.A.
89.2
89.7
N.A.
74.7
75.1
79.2
71.5
N.A.
58.4
55.4
47.5
62.2
Protein Similarity:
100
N.A.
98.2
85.8
N.A.
94
94.2
N.A.
81.9
83.3
88.8
84.2
N.A.
75.5
69.5
63.1
76.8
P-Site Identity:
100
N.A.
93.3
20
N.A.
86.6
80
N.A.
86.6
26.6
80
46.6
N.A.
46.6
20
6.6
40
P-Site Similarity:
100
N.A.
93.3
20
N.A.
93.3
93.3
N.A.
93.3
40
93.3
53.3
N.A.
60
20
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
72
0
0
8
0
65
0
0
15
0
79
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
43
0
0
22
0
0
8
8
65
0
22
% D
% Glu:
0
0
0
0
8
0
0
0
0
15
0
8
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
65
0
0
8
0
15
0
22
0
0
0
8
65
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
72
0
0
0
8
43
0
0
0
0
43
22
0
8
0
% I
% Lys:
0
0
0
0
8
8
8
0
0
29
22
15
0
0
0
% K
% Leu:
22
65
8
0
0
8
0
0
0
0
15
0
22
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
0
8
15
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
29
0
0
0
% Q
% Arg:
0
15
0
0
15
0
50
0
0
29
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
15
8
0
8
0
0
0
0
8
% S
% Thr:
8
0
15
15
0
15
8
43
8
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
15
0
0
22
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _