KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADHFE1
All Species:
27.27
Human Site:
Y107
Identified Species:
46.15
UniProt:
Q8IWW8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWW8
NP_653251.2
467
50308
Y107
N
G
I
P
F
T
V
Y
D
N
V
R
V
E
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094680
467
50184
Y107
N
G
I
P
F
T
V
Y
D
N
V
R
V
E
P
Dog
Lupus familis
XP_849448
419
45266
E73
P
T
D
R
S
F
M
E
A
I
E
F
V
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0N6
465
49919
Y105
N
G
I
S
F
Q
V
Y
D
D
V
R
V
E
P
Rat
Rattus norvegicus
Q4QQW3
467
50207
Y107
N
G
I
S
F
Q
V
Y
D
N
V
R
V
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511833
542
59240
Y182
N
G
I
N
F
K
V
Y
N
N
V
R
V
E
P
Chicken
Gallus gallus
XP_424090
419
45207
D73
P
T
D
Q
S
F
L
D
A
I
E
F
A
K
K
Frog
Xenopus laevis
Q08B39
463
50154
Y103
N
G
I
N
F
K
L
Y
D
S
V
R
V
E
P
Zebra Danio
Brachydanio rerio
NP_996969
471
50630
Y111
H
G
V
K
H
K
L
Y
E
D
V
R
V
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W265
464
49999
Y104
N
G
I
N
Y
E
V
Y
D
E
T
R
V
E
P
Honey Bee
Apis mellifera
XP_624450
418
45967
K72
E
P
T
D
Q
S
L
K
D
C
I
E
F
V
K
Nematode Worm
Caenorhab. elegans
Q9U2M4
465
50487
F104
V
N
I
E
Y
E
V
F
D
D
V
L
I
E
P
Sea Urchin
Strong. purpuratus
XP_780928
479
51618
F119
A
K
V
N
Y
E
V
F
D
S
V
R
V
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10127
382
41124
L36
N
K
D
Y
K
K
A
L
I
V
T
D
P
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
83.3
N.A.
89.2
89.7
N.A.
74.7
75.1
79.2
71.5
N.A.
58.4
55.4
47.5
62.2
Protein Similarity:
100
N.A.
98.2
85.8
N.A.
94
94.2
N.A.
81.9
83.3
88.8
84.2
N.A.
75.5
69.5
63.1
76.8
P-Site Identity:
100
N.A.
100
6.6
N.A.
80
86.6
N.A.
80
0
73.3
46.6
N.A.
66.6
6.6
40
46.6
P-Site Similarity:
100
N.A.
100
20
N.A.
86.6
86.6
N.A.
86.6
13.3
86.6
80
N.A.
73.3
26.6
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
15
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
22
8
0
0
0
8
65
22
0
8
0
0
0
% D
% Glu:
8
0
0
8
0
22
0
8
8
8
15
8
0
72
0
% E
% Phe:
0
0
0
0
43
15
0
15
0
0
0
15
8
0
0
% F
% Gly:
0
58
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
58
0
0
0
0
0
8
15
8
0
8
0
8
% I
% Lys:
0
15
0
8
8
29
0
8
0
0
0
0
0
15
22
% K
% Leu:
0
0
0
0
0
0
29
8
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
58
8
0
29
0
0
0
0
8
29
0
0
0
0
0
% N
% Pro:
15
8
0
15
0
0
0
0
0
0
0
0
8
0
72
% P
% Gln:
0
0
0
8
8
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
65
0
0
0
% R
% Ser:
0
0
0
15
15
8
0
0
0
15
0
0
0
0
0
% S
% Thr:
0
15
8
0
0
15
0
0
0
0
15
0
0
0
0
% T
% Val:
8
0
15
0
0
0
58
0
0
8
65
0
72
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
22
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _