KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADHFE1
All Species:
26.36
Human Site:
Y163
Identified Species:
44.62
UniProt:
Q8IWW8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWW8
NP_653251.2
467
50308
Y163
P
H
S
D
F
L
D
Y
V
S
A
P
I
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094680
467
50184
Y163
P
H
S
D
F
L
D
Y
V
S
A
P
I
G
K
Dog
Lupus familis
XP_849448
419
45266
V128
G
K
G
K
P
V
S
V
P
L
K
P
L
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0N6
465
49919
Y161
P
H
S
E
F
L
D
Y
V
N
A
P
I
G
K
Rat
Rattus norvegicus
Q4QQW3
467
50207
Y163
P
H
S
E
F
L
D
Y
V
N
A
P
I
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511833
542
59240
Y238
P
D
S
D
F
L
D
Y
V
N
A
P
I
G
K
Chicken
Gallus gallus
XP_424090
419
45207
V128
G
K
G
K
A
V
T
V
P
L
K
P
L
I
A
Frog
Xenopus laevis
Q08B39
463
50154
Y159
P
D
S
D
F
L
D
Y
V
N
P
P
I
G
K
Zebra Danio
Brachydanio rerio
NP_996969
471
50630
F167
P
E
A
E
F
L
D
F
V
N
A
P
I
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W265
464
49999
Y160
A
N
A
E
F
L
D
Y
V
N
C
P
I
G
R
Honey Bee
Apis mellifera
XP_624450
418
45967
T127
I
G
K
E
K
P
I
T
I
Q
L
K
P
L
V
Nematode Worm
Caenorhab. elegans
Q9U2M4
465
50487
F160
P
E
A
D
F
L
D
F
V
G
P
P
F
G
K
Sea Urchin
Strong. purpuratus
XP_780928
479
51618
F175
R
D
A
D
F
L
D
F
V
N
A
P
V
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10127
382
41124
E91
V
L
K
E
Q
N
S
E
I
V
V
S
I
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
83.3
N.A.
89.2
89.7
N.A.
74.7
75.1
79.2
71.5
N.A.
58.4
55.4
47.5
62.2
Protein Similarity:
100
N.A.
98.2
85.8
N.A.
94
94.2
N.A.
81.9
83.3
88.8
84.2
N.A.
75.5
69.5
63.1
76.8
P-Site Identity:
100
N.A.
100
6.6
N.A.
86.6
86.6
N.A.
86.6
6.6
80
66.6
N.A.
53.3
0
60
60
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
93.3
20
86.6
93.3
N.A.
86.6
13.3
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
29
0
8
0
0
0
0
0
50
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
22
0
43
0
0
72
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
43
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
72
0
0
22
0
0
0
0
8
0
0
% F
% Gly:
15
8
15
0
0
0
0
0
0
8
0
0
0
79
8
% G
% His:
0
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
15
0
0
0
65
15
0
% I
% Lys:
0
15
15
15
8
0
0
0
0
0
15
8
0
0
65
% K
% Leu:
0
8
0
0
0
72
0
0
0
15
8
0
15
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
50
0
0
0
0
0
% N
% Pro:
58
0
0
0
8
8
0
0
15
0
15
86
8
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
43
0
0
0
15
0
0
15
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
15
0
15
72
8
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _