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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPP2
All Species:
37.27
Human Site:
S146
Identified Species:
68.33
UniProt:
Q8IWX5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX5
NP_689599.2
399
44741
S146
L
K
W
P
R
P
S
S
P
P
V
V
K
L
E
Chimpanzee
Pan troglodytes
XP_526109
399
44704
S146
L
K
W
P
R
P
S
S
P
P
V
V
K
L
E
Rhesus Macaque
Macaca mulatta
XP_001107876
399
44723
S146
L
K
W
P
R
P
S
S
P
P
V
V
K
L
E
Dog
Lupus familis
XP_547850
445
49494
S192
I
R
W
P
R
P
A
S
P
P
V
V
K
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q810K3
354
40229
I112
V
R
L
E
K
R
I
I
A
E
Y
G
M
P
S
Rat
Rattus norvegicus
Q99P55
430
47631
S177
I
R
W
P
R
P
A
S
P
P
V
I
K
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505813
313
34340
L71
D
S
A
E
G
I
P
L
P
P
S
T
V
P
N
Chicken
Gallus gallus
XP_422628
488
52623
S239
L
K
W
P
R
P
L
S
P
P
V
V
K
L
E
Frog
Xenopus laevis
NP_001091137
400
44326
S151
L
K
W
P
R
P
S
S
P
P
V
V
K
L
E
Zebra Danio
Brachydanio rerio
XP_002664750
415
46244
S158
L
K
L
P
R
P
P
S
P
P
V
V
K
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122506
399
45587
C133
I
C
W
A
R
P
A
C
P
P
A
V
R
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787135
411
46436
S162
I
R
W
P
R
P
L
S
P
P
V
A
P
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23501
404
46470
S139
W
C
L
P
R
P
K
S
P
P
V
D
R
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
36.8
N.A.
81.1
37.2
N.A.
43.1
50.2
53
47.7
N.A.
N.A.
33.3
N.A.
34.7
Protein Similarity:
100
100
97.4
56.4
N.A.
85.2
57.6
N.A.
55.1
61.2
68
62.8
N.A.
N.A.
56.6
N.A.
55.2
P-Site Identity:
100
100
100
80
N.A.
0
73.3
N.A.
13.3
93.3
100
86.6
N.A.
N.A.
46.6
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
13.3
93.3
100
86.6
N.A.
N.A.
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
24
0
8
0
8
8
0
0
0
% A
% Cys:
0
16
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
16
0
0
0
0
0
8
0
0
0
0
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
31
0
0
0
0
8
8
8
0
0
0
8
0
8
0
% I
% Lys:
0
47
0
0
8
0
8
0
0
0
0
0
62
0
0
% K
% Leu:
47
0
24
0
0
0
16
8
0
0
0
0
0
77
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
77
0
85
16
0
93
93
0
0
8
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
31
0
0
85
8
0
0
0
0
0
0
16
0
0
% R
% Ser:
0
8
0
0
0
0
31
77
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
8
0
0
0
0
0
0
0
0
0
77
62
8
0
0
% V
% Trp:
8
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _