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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGPP2 All Species: 10.91
Human Site: S301 Identified Species: 20
UniProt: Q8IWX5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWX5 NP_689599.2 399 44741 S301 N H F F Q L V S K P A E S L P
Chimpanzee Pan troglodytes XP_526109 399 44704 S301 N H F F Q L V S K P A E S L P
Rhesus Macaque Macaca mulatta XP_001107876 399 44723 S301 N H S F Q L V S Q P A E P L P
Dog Lupus familis XP_547850 445 49494 L347 T Y N M G L I L D P S L D I L
Cat Felis silvestris
Mouse Mus musculus Q810K3 354 40229 Q266 T P S L P V I Q N I P P L T T
Rat Rattus norvegicus Q99P55 430 47631 L332 A Y N L G I S L D P S L H T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505813 313 34340 R225 E P T K Y I L R G I P P I T W
Chicken Gallus gallus XP_422628 488 52623 A394 N N Q Y V A P A H V G S T M A
Frog Xenopus laevis NP_001091137 400 44326 M306 G K L E L N S M P S A H F P L
Zebra Danio Brachydanio rerio XP_002664750 415 46244 F313 N E R L G L T F Y L T G P F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122506 399 45587 S288 N Y N I G S M S A P T K S P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787135 411 46436 P317 C H Q Q G I P P M Y D E L P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23501 404 46470 E294 D C S D W L T E R Y G W N L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.7 36.8 N.A. 81.1 37.2 N.A. 43.1 50.2 53 47.7 N.A. N.A. 33.3 N.A. 34.7
Protein Similarity: 100 100 97.4 56.4 N.A. 85.2 57.6 N.A. 55.1 61.2 68 62.8 N.A. N.A. 56.6 N.A. 55.2
P-Site Identity: 100 100 80 13.3 N.A. 0 6.6 N.A. 0 6.6 6.6 20 N.A. N.A. 33.3 N.A. 13.3
P-Site Similarity: 100 100 86.6 40 N.A. 13.3 26.6 N.A. 13.3 40 6.6 20 N.A. N.A. 53.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 0 8 8 0 31 0 0 0 8 % A
% Cys: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 0 0 16 0 8 0 8 0 0 % D
% Glu: 8 8 0 8 0 0 0 8 0 0 0 31 0 0 0 % E
% Phe: 0 0 16 24 0 0 0 8 0 0 0 0 8 8 0 % F
% Gly: 8 0 0 0 39 0 0 0 8 0 16 8 0 0 0 % G
% His: 0 31 0 0 0 0 0 0 8 0 0 8 8 0 0 % H
% Ile: 0 0 0 8 0 24 16 0 0 16 0 0 8 8 0 % I
% Lys: 0 8 0 8 0 0 0 0 16 0 0 8 0 0 0 % K
% Leu: 0 0 8 24 8 47 8 16 0 8 0 16 16 31 24 % L
% Met: 0 0 0 8 0 0 8 8 8 0 0 0 0 8 0 % M
% Asn: 47 8 24 0 0 8 0 0 8 0 0 0 8 0 0 % N
% Pro: 0 16 0 0 8 0 16 8 8 47 16 16 16 24 39 % P
% Gln: 0 0 16 8 24 0 0 8 8 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 8 8 0 0 0 0 0 0 % R
% Ser: 0 0 24 0 0 8 16 31 0 8 16 8 24 0 8 % S
% Thr: 16 0 8 0 0 0 16 0 0 0 16 0 8 24 8 % T
% Val: 0 0 0 0 8 8 24 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 8 % W
% Tyr: 0 24 0 8 8 0 0 0 8 16 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _