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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPP2
All Species:
16.06
Human Site:
S346
Identified Species:
29.44
UniProt:
Q8IWX5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX5
NP_689599.2
399
44741
S346
R
Q
L
V
Q
N
L
S
L
Q
V
L
Y
S
W
Chimpanzee
Pan troglodytes
XP_526109
399
44704
S346
R
Q
L
V
Q
N
L
S
L
Q
V
L
Y
S
W
Rhesus Macaque
Macaca mulatta
XP_001107876
399
44723
S346
R
Q
L
V
Q
N
L
S
L
Q
V
L
Y
S
W
Dog
Lupus familis
XP_547850
445
49494
I392
D
I
M
K
K
I
T
I
P
L
A
C
K
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q810K3
354
40229
F306
K
L
S
L
Q
V
L
F
S
W
F
K
V
V
T
Rat
Rattus norvegicus
Q99P55
430
47631
I377
D
I
M
K
K
V
T
I
P
L
A
C
K
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505813
313
34340
Y265
S
L
S
L
Q
V
L
Y
S
W
F
R
V
A
T
Chicken
Gallus gallus
XP_422628
488
52623
V435
R
Q
L
M
K
N
V
V
L
R
V
L
C
Y
C
Frog
Xenopus laevis
NP_001091137
400
44326
S348
R
F
L
A
K
T
L
S
L
Q
A
L
G
K
W
Zebra Danio
Brachydanio rerio
XP_002664750
415
46244
S356
R
Q
T
V
R
F
V
S
L
R
V
L
C
W
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122506
399
45587
I338
I
Y
G
T
I
C
A
I
L
K
I
N
S
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787135
411
46436
I359
S
H
V
T
F
K
T
I
I
L
G
I
L
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23501
404
46470
D347
I
K
L
L
R
F
H
D
D
R
S
E
K
V
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
36.8
N.A.
81.1
37.2
N.A.
43.1
50.2
53
47.7
N.A.
N.A.
33.3
N.A.
34.7
Protein Similarity:
100
100
97.4
56.4
N.A.
85.2
57.6
N.A.
55.1
61.2
68
62.8
N.A.
N.A.
56.6
N.A.
55.2
P-Site Identity:
100
100
100
0
N.A.
13.3
0
N.A.
13.3
46.6
53.3
46.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
26.6
20
N.A.
26.6
73.3
60
66.6
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
0
24
0
0
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
16
16
0
8
% C
% Asp:
16
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
8
16
0
8
0
0
16
0
0
0
16
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
16
16
0
0
8
8
0
31
8
0
8
8
0
8
8
% I
% Lys:
8
8
0
16
31
8
0
0
0
8
0
8
24
16
0
% K
% Leu:
0
16
47
24
0
0
47
0
54
24
0
47
8
8
0
% L
% Met:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
31
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% P
% Gln:
0
39
0
0
39
0
0
0
0
31
0
0
0
0
0
% Q
% Arg:
47
0
0
0
16
0
0
0
0
24
0
8
0
0
0
% R
% Ser:
16
0
16
0
0
0
0
39
16
0
8
0
8
31
0
% S
% Thr:
0
0
8
16
0
8
24
0
0
0
0
0
0
0
16
% T
% Val:
0
0
8
31
0
24
16
8
0
0
39
0
16
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
31
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
0
24
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _