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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPP2
All Species:
31.52
Human Site:
T277
Identified Species:
57.78
UniProt:
Q8IWX5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX5
NP_689599.2
399
44741
T277
Y
S
P
T
R
A
D
T
T
T
I
L
A
A
G
Chimpanzee
Pan troglodytes
XP_526109
399
44704
T277
Y
S
P
T
R
A
D
T
T
T
I
L
A
A
G
Rhesus Macaque
Macaca mulatta
XP_001107876
399
44723
T277
Y
S
P
T
R
A
D
T
T
T
I
L
A
A
G
Dog
Lupus familis
XP_547850
445
49494
T323
W
S
T
S
R
G
D
T
A
E
I
L
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q810K3
354
40229
V242
I
V
A
A
G
A
G
V
T
L
G
F
W
I
N
Rat
Rattus norvegicus
Q99P55
430
47631
T308
W
S
T
S
R
G
D
T
A
E
I
L
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505813
313
34340
A201
T
T
I
L
A
A
G
A
G
G
T
L
G
F
W
Chicken
Gallus gallus
XP_422628
488
52623
T370
Y
S
P
T
R
G
D
T
T
T
I
L
G
A
G
Frog
Xenopus laevis
NP_001091137
400
44326
T282
Y
S
T
T
R
A
D
T
T
T
I
I
G
V
A
Zebra Danio
Brachydanio rerio
XP_002664750
415
46244
T289
Y
S
T
T
R
G
D
T
T
I
I
L
A
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122506
399
45587
T264
W
T
P
T
R
G
D
T
T
M
V
V
S
V
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787135
411
46436
T293
W
S
S
T
R
A
D
T
I
V
I
M
G
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23501
404
46470
C270
H
V
R
P
I
D
E
C
P
C
F
E
D
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
36.8
N.A.
81.1
37.2
N.A.
43.1
50.2
53
47.7
N.A.
N.A.
33.3
N.A.
34.7
Protein Similarity:
100
100
97.4
56.4
N.A.
85.2
57.6
N.A.
55.1
61.2
68
62.8
N.A.
N.A.
56.6
N.A.
55.2
P-Site Identity:
100
100
100
46.6
N.A.
13.3
46.6
N.A.
13.3
86.6
66.6
66.6
N.A.
N.A.
40
N.A.
46.6
P-Site Similarity:
100
100
100
66.6
N.A.
13.3
66.6
N.A.
20
86.6
73.3
66.6
N.A.
N.A.
73.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
54
0
8
16
0
0
0
31
31
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
8
77
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
16
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% F
% Gly:
0
0
0
0
8
39
16
0
8
8
8
0
47
0
47
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
8
0
0
0
8
8
70
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
8
0
62
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
39
8
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
77
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
70
8
16
0
0
0
0
0
0
0
0
8
24
8
% S
% Thr:
8
16
31
62
0
0
0
77
62
39
8
0
0
0
16
% T
% Val:
0
16
0
0
0
0
0
8
0
8
8
8
0
24
8
% V
% Trp:
31
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% W
% Tyr:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _