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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPP2
All Species:
12.73
Human Site:
Y116
Identified Species:
23.33
UniProt:
Q8IWX5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX5
NP_689599.2
399
44741
Y116
T
H
W
N
I
D
P
Y
L
S
R
R
L
I
I
Chimpanzee
Pan troglodytes
XP_526109
399
44704
Y116
T
H
W
N
I
D
P
Y
L
S
R
R
L
I
I
Rhesus Macaque
Macaca mulatta
XP_001107876
399
44723
Y116
T
H
W
N
I
D
P
Y
L
S
R
R
L
I
I
Dog
Lupus familis
XP_547850
445
49494
L162
W
I
W
N
L
D
A
L
V
G
R
R
L
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q810K3
354
40229
L82
R
L
V
V
I
W
V
L
V
M
Y
I
G
Q
V
Rat
Rattus norvegicus
Q99P55
430
47631
F147
W
I
W
N
L
D
P
F
V
G
R
R
L
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505813
313
34340
P41
P
S
V
T
V
S
S
P
S
P
R
P
V
R
F
Chicken
Gallus gallus
XP_422628
488
52623
S209
I
Y
W
N
I
D
H
S
V
S
R
R
M
I
I
Frog
Xenopus laevis
NP_001091137
400
44326
F121
T
Y
W
N
L
D
P
F
I
G
H
R
L
V
V
Zebra Danio
Brachydanio rerio
XP_002664750
415
46244
F128
I
H
W
N
L
D
P
F
L
C
R
R
L
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122506
399
45587
A103
W
F
W
N
I
D
G
A
V
G
R
R
V
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787135
411
46436
W132
W
F
F
N
I
S
P
W
V
I
R
R
V
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23501
404
46470
D109
P
V
W
L
G
Y
R
D
L
T
R
D
M
I
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
36.8
N.A.
81.1
37.2
N.A.
43.1
50.2
53
47.7
N.A.
N.A.
33.3
N.A.
34.7
Protein Similarity:
100
100
97.4
56.4
N.A.
85.2
57.6
N.A.
55.1
61.2
68
62.8
N.A.
N.A.
56.6
N.A.
55.2
P-Site Identity:
100
100
100
40
N.A.
6.6
53.3
N.A.
6.6
60
46.6
60
N.A.
N.A.
40
N.A.
40
P-Site Similarity:
100
100
100
66.6
N.A.
20
80
N.A.
20
80
86.6
80
N.A.
N.A.
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
70
0
8
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
16
8
0
0
0
0
24
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
0
8
0
0
31
0
0
8
0
0
% G
% His:
0
31
0
0
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
16
16
0
0
54
0
0
0
8
8
0
8
0
47
39
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
31
0
0
16
39
0
0
0
54
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
16
0
0
% M
% Asn:
0
0
0
77
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
16
0
0
0
0
0
54
8
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
0
8
0
0
0
85
77
0
8
0
% R
% Ser:
0
8
0
0
0
16
8
8
8
31
0
0
0
0
0
% S
% Thr:
31
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
8
16
8
8
0
8
0
47
0
0
0
24
39
24
% V
% Trp:
31
0
77
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
0
8
0
24
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _