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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPP2
All Species:
18.79
Human Site:
Y269
Identified Species:
34.44
UniProt:
Q8IWX5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX5
NP_689599.2
399
44741
Y269
Y
N
Y
P
V
S
D
Y
Y
S
P
T
R
A
D
Chimpanzee
Pan troglodytes
XP_526109
399
44704
Y269
Y
N
Y
P
V
S
D
Y
Y
S
P
T
R
A
D
Rhesus Macaque
Macaca mulatta
XP_001107876
399
44723
Y269
Y
N
Y
P
V
S
D
Y
Y
S
P
T
R
A
D
Dog
Lupus familis
XP_547850
445
49494
T315
I
F
S
F
T
L
D
T
W
S
T
S
R
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q810K3
354
40229
T234
P
T
R
A
D
T
T
T
I
V
A
A
G
A
G
Rat
Rattus norvegicus
Q99P55
430
47631
T300
I
F
S
F
T
L
D
T
W
S
T
S
R
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505813
313
34340
T193
Y
S
P
T
R
A
D
T
T
T
I
L
A
A
G
Chicken
Gallus gallus
XP_422628
488
52623
Y362
Y
N
Y
P
K
L
D
Y
Y
S
P
T
R
G
D
Frog
Xenopus laevis
NP_001091137
400
44326
H274
Y
N
Y
P
K
M
N
H
Y
S
T
T
R
A
D
Zebra Danio
Brachydanio rerio
XP_002664750
415
46244
H281
Y
T
Y
P
E
L
D
H
Y
S
T
T
R
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122506
399
45587
K256
V
Y
Y
P
C
S
K
K
W
T
P
T
R
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787135
411
46436
G285
I
I
Y
P
T
Q
D
G
W
S
S
T
R
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23501
404
46470
N262
W
G
L
F
I
L
F
N
H
V
R
P
I
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
36.8
N.A.
81.1
37.2
N.A.
43.1
50.2
53
47.7
N.A.
N.A.
33.3
N.A.
34.7
Protein Similarity:
100
100
97.4
56.4
N.A.
85.2
57.6
N.A.
55.1
61.2
68
62.8
N.A.
N.A.
56.6
N.A.
55.2
P-Site Identity:
100
100
100
26.6
N.A.
6.6
26.6
N.A.
20
80
66.6
60
N.A.
N.A.
46.6
N.A.
53.3
P-Site Similarity:
100
100
100
40
N.A.
13.3
40
N.A.
40
80
80
66.6
N.A.
N.A.
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
0
8
8
8
54
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
70
0
0
0
0
0
0
8
77
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
16
0
24
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
0
8
39
16
% G
% His:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
0
% H
% Ile:
24
8
0
0
8
0
0
0
8
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
16
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
39
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
39
0
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
62
0
0
0
0
0
0
39
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
8
0
77
0
0
% R
% Ser:
0
8
16
0
0
31
0
0
0
70
8
16
0
0
0
% S
% Thr:
0
16
0
8
24
8
8
31
8
16
31
62
0
0
0
% T
% Val:
8
0
0
0
24
0
0
0
0
16
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% W
% Tyr:
54
8
62
0
0
0
0
31
47
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _