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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPP2
All Species:
11.21
Human Site:
Y75
Identified Species:
20.56
UniProt:
Q8IWX5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX5
NP_689599.2
399
44741
Y75
R
A
A
A
P
E
A
Y
V
Q
K
Y
V
V
K
Chimpanzee
Pan troglodytes
XP_526109
399
44704
Y75
R
A
A
A
P
E
A
Y
V
Q
K
Y
V
V
K
Rhesus Macaque
Macaca mulatta
XP_001107876
399
44723
Y75
R
A
A
A
P
E
A
Y
V
Q
K
Y
V
V
K
Dog
Lupus familis
XP_547850
445
49494
E121
R
N
S
L
T
D
E
E
G
E
L
A
H
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q810K3
354
40229
Y41
H
V
V
K
N
Y
F
Y
Y
Y
L
F
R
F
S
Rat
Rattus norvegicus
Q99P55
430
47631
E106
R
N
S
L
T
G
E
E
G
E
L
A
K
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505813
313
34340
Chicken
Gallus gallus
XP_422628
488
52623
C168
G
G
R
G
P
Q
G
C
V
Q
K
Y
V
V
K
Frog
Xenopus laevis
NP_001091137
400
44326
I80
N
G
A
P
K
Q
G
I
A
K
K
Y
Q
V
Q
Zebra Danio
Brachydanio rerio
XP_002664750
415
46244
P87
D
N
K
V
E
G
H
P
R
P
H
Y
V
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122506
399
45587
Y62
Q
K
Q
S
S
N
I
Y
N
T
N
Y
T
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787135
411
46436
A91
P
N
A
T
V
S
A
A
P
V
E
Y
R
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23501
404
46470
H68
D
N
Q
S
D
F
V
H
S
L
Q
K
K
H
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
36.8
N.A.
81.1
37.2
N.A.
43.1
50.2
53
47.7
N.A.
N.A.
33.3
N.A.
34.7
Protein Similarity:
100
100
97.4
56.4
N.A.
85.2
57.6
N.A.
55.1
61.2
68
62.8
N.A.
N.A.
56.6
N.A.
55.2
P-Site Identity:
100
100
100
13.3
N.A.
6.6
13.3
N.A.
0
53.3
26.6
26.6
N.A.
N.A.
13.3
N.A.
26.6
P-Site Similarity:
100
100
100
33.3
N.A.
13.3
26.6
N.A.
0
60
46.6
26.6
N.A.
N.A.
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
39
24
0
0
31
8
8
0
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
24
16
16
0
16
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
8
0
8
0
% F
% Gly:
8
16
0
8
0
16
16
0
16
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
8
8
0
0
8
0
8
8
8
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% I
% Lys:
0
8
8
8
8
0
0
0
0
8
39
8
16
0
39
% K
% Leu:
0
0
0
16
0
0
0
0
0
8
24
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
39
0
0
8
8
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
0
0
8
31
0
0
8
8
8
0
0
0
0
0
% P
% Gln:
8
0
16
0
0
16
0
0
0
31
8
0
8
0
8
% Q
% Arg:
39
0
8
0
0
0
0
0
8
0
0
0
16
0
8
% R
% Ser:
0
0
16
16
8
8
0
0
8
0
0
0
0
0
24
% S
% Thr:
0
0
0
8
16
0
0
0
0
8
0
0
8
0
8
% T
% Val:
0
8
8
8
8
0
8
0
31
8
0
0
39
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
39
8
8
0
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _