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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPP2
All Species:
22.12
Human Site:
Y79
Identified Species:
40.56
UniProt:
Q8IWX5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX5
NP_689599.2
399
44741
Y79
P
E
A
Y
V
Q
K
Y
V
V
K
N
Y
F
Y
Chimpanzee
Pan troglodytes
XP_526109
399
44704
Y79
P
E
A
Y
V
Q
K
Y
V
V
K
N
Y
F
Y
Rhesus Macaque
Macaca mulatta
XP_001107876
399
44723
Y79
P
E
A
Y
V
Q
K
Y
V
V
K
N
Y
F
Y
Dog
Lupus familis
XP_547850
445
49494
A125
T
D
E
E
G
E
L
A
H
V
S
N
W
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q810K3
354
40229
F45
N
Y
F
Y
Y
Y
L
F
R
F
S
A
A
L
G
Rat
Rattus norvegicus
Q99P55
430
47631
A110
T
G
E
E
G
E
L
A
K
V
S
N
L
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505813
313
34340
Chicken
Gallus gallus
XP_422628
488
52623
Y172
P
Q
G
C
V
Q
K
Y
V
V
K
N
Y
F
Y
Frog
Xenopus laevis
NP_001091137
400
44326
Y84
K
Q
G
I
A
K
K
Y
Q
V
Q
N
Y
F
L
Zebra Danio
Brachydanio rerio
XP_002664750
415
46244
Y91
E
G
H
P
R
P
H
Y
V
V
K
N
W
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122506
399
45587
Y66
S
N
I
Y
N
T
N
Y
T
I
T
N
Y
F
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787135
411
46436
Y95
V
S
A
A
P
V
E
Y
R
V
H
N
K
F
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23501
404
46470
K72
D
F
V
H
S
L
Q
K
K
H
R
T
P
F
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
36.8
N.A.
81.1
37.2
N.A.
43.1
50.2
53
47.7
N.A.
N.A.
33.3
N.A.
34.7
Protein Similarity:
100
100
97.4
56.4
N.A.
85.2
57.6
N.A.
55.1
61.2
68
62.8
N.A.
N.A.
56.6
N.A.
55.2
P-Site Identity:
100
100
100
13.3
N.A.
6.6
13.3
N.A.
0
80
40
33.3
N.A.
N.A.
33.3
N.A.
33.3
P-Site Similarity:
100
100
100
33.3
N.A.
13.3
20
N.A.
0
86.6
60
46.6
N.A.
N.A.
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
8
8
0
0
16
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
24
16
16
0
16
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
8
0
0
0
0
8
0
8
0
0
0
62
8
% F
% Gly:
0
16
16
0
16
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
8
8
0
0
8
0
8
8
8
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
39
8
16
0
39
0
8
0
0
% K
% Leu:
0
0
0
0
0
8
24
0
0
0
0
0
8
16
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
8
0
8
0
0
0
0
77
0
0
0
% N
% Pro:
31
0
0
8
8
8
0
0
0
0
0
0
8
16
0
% P
% Gln:
0
16
0
0
0
31
8
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
16
0
8
0
0
0
8
% R
% Ser:
8
8
0
0
8
0
0
0
0
0
24
0
0
0
0
% S
% Thr:
16
0
0
0
0
8
0
0
8
0
8
8
0
0
0
% T
% Val:
8
0
8
0
31
8
0
0
39
70
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
16
% W
% Tyr:
0
8
0
39
8
8
0
62
0
0
0
0
47
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _