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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45B
All Species:
19.09
Human Site:
S567
Identified Species:
38.18
UniProt:
Q8IWX7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX7
NP_001028748.1
931
103733
S567
E
L
A
K
A
G
T
S
D
K
T
I
L
Y
S
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
S565
M
F
E
L
A
K
T
S
D
K
T
I
L
Y
S
Rhesus Macaque
Macaca mulatta
XP_001113905
929
103569
S565
M
F
E
L
A
K
T
S
D
K
T
I
L
Y
S
Dog
Lupus familis
XP_537726
943
104653
A565
M
F
E
L
A
K
T
A
D
K
T
I
L
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGY6
931
103619
S567
E
L
A
K
A
R
T
S
D
K
T
I
L
Y
S
Rat
Rattus norvegicus
Q32PZ3
944
103222
E581
L
F
Q
L
S
R
S
E
E
R
S
V
L
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
S556
M
F
E
L
A
K
T
S
D
K
T
I
L
Y
S
Frog
Xenopus laevis
NP_001087472
927
103492
S562
M
F
E
L
C
K
T
S
D
K
T
I
L
Y
S
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
N569
M
F
E
L
T
K
S
N
D
K
T
I
L
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
G570
L
M
D
L
A
R
G
G
N
Q
S
C
L
Y
G
Honey Bee
Apis mellifera
XP_396019
942
106098
G567
M
I
E
L
A
K
T
G
D
Q
S
V
V
Y
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
S565
L
M
D
L
S
K
T
S
D
K
T
V
L
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.9
95.5
N.A.
94.9
55.4
N.A.
N.A.
73.5
78.4
71.3
N.A.
34.7
38.1
N.A.
44.1
Protein Similarity:
100
98.5
99.1
97.5
N.A.
98.1
73.9
N.A.
N.A.
81.2
90.3
85
N.A.
58.6
62
N.A.
68.6
P-Site Identity:
100
66.6
66.6
60
N.A.
93.3
6.6
N.A.
N.A.
66.6
60
40
N.A.
20
26.6
N.A.
46.6
P-Site Similarity:
100
66.6
66.6
66.6
N.A.
93.3
60
N.A.
N.A.
66.6
60
60
N.A.
46.6
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
67
0
0
9
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
17
0
0
0
0
0
84
0
0
0
0
0
0
% D
% Glu:
17
0
59
0
0
0
0
9
9
0
0
0
0
0
0
% E
% Phe:
0
59
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
9
9
17
0
0
0
0
0
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
67
0
0
0
% I
% Lys:
0
0
0
17
0
67
0
0
0
75
0
0
0
0
0
% K
% Leu:
25
17
0
84
0
0
0
0
0
0
0
0
92
0
0
% L
% Met:
59
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
17
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
25
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
17
0
17
59
0
0
25
0
0
0
59
% S
% Thr:
0
0
0
0
9
0
75
0
0
0
75
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
25
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
92
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _