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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45B
All Species:
26.67
Human Site:
T669
Identified Species:
53.33
UniProt:
Q8IWX7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX7
NP_001028748.1
931
103733
T669
D
N
P
K
D
R
G
T
I
V
A
Q
G
G
G
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
T667
D
N
P
K
D
R
G
T
I
V
A
Q
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001113905
929
103569
T667
D
N
P
K
D
R
G
T
I
V
A
Q
G
G
G
Dog
Lupus familis
XP_537726
943
104653
T667
D
N
P
K
D
R
G
T
I
V
A
Q
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGY6
931
103619
T669
D
N
P
K
D
R
G
T
I
V
A
Q
G
G
G
Rat
Rattus norvegicus
Q32PZ3
944
103222
T683
E
E
V
E
D
R
G
T
V
V
A
Q
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
T658
D
D
P
K
D
R
G
T
I
V
A
Q
G
G
G
Frog
Xenopus laevis
NP_001087472
927
103492
I664
D
E
P
K
D
R
G
I
I
V
A
Q
G
G
G
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
I671
E
D
V
K
D
R
G
I
I
V
A
Q
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
K668
G
L
K
E
L
R
G
K
V
V
Q
E
G
G
V
Honey Bee
Apis mellifera
XP_396019
942
106098
I665
S
Q
Q
E
V
R
G
I
I
V
Q
Q
G
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
L663
E
D
I
D
H
R
G
L
V
V
Q
Q
G
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.9
95.5
N.A.
94.9
55.4
N.A.
N.A.
73.5
78.4
71.3
N.A.
34.7
38.1
N.A.
44.1
Protein Similarity:
100
98.5
99.1
97.5
N.A.
98.1
73.9
N.A.
N.A.
81.2
90.3
85
N.A.
58.6
62
N.A.
68.6
P-Site Identity:
100
100
100
100
N.A.
100
66.6
N.A.
N.A.
93.3
86.6
73.3
N.A.
33.3
46.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
100
86.6
86.6
N.A.
53.3
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
25
0
9
75
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
25
17
0
25
0
0
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
100
0
0
0
0
0
100
100
75
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
25
75
0
0
0
0
0
0
% I
% Lys:
0
0
9
67
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
25
92
0
0
0
% Q
% Arg:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% T
% Val:
0
0
17
0
9
0
0
0
25
100
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _