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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45B
All Species:
26.06
Human Site:
Y22
Identified Species:
52.12
UniProt:
Q8IWX7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWX7
NP_001028748.1
931
103733
Y22
R
H
F
Q
L
Q
D
Y
K
A
A
T
N
S
Y
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
Y22
R
H
F
Q
L
Q
D
Y
K
A
A
T
K
S
Y
Rhesus Macaque
Macaca mulatta
XP_001113905
929
103569
Y22
R
H
F
Q
L
Q
D
Y
K
A
A
T
K
S
Y
Dog
Lupus familis
XP_537726
943
104653
Y22
R
H
F
Q
L
Q
D
Y
K
A
A
T
K
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGY6
931
103619
Y22
R
H
F
Q
L
Q
D
Y
K
A
A
T
K
S
Y
Rat
Rattus norvegicus
Q32PZ3
944
103222
Y37
E
L
F
K
C
G
D
Y
E
G
A
L
T
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
Y43
K
Y
F
Q
A
S
D
Y
E
R
A
A
Q
S
Y
Frog
Xenopus laevis
NP_001087472
927
103492
Y20
K
Y
F
Q
S
N
D
Y
G
N
A
I
E
C
Y
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
Q27
F
Q
A
G
E
I
D
Q
A
I
D
C
Y
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
W29
E
A
F
K
A
S
R
W
E
E
A
V
E
H
Y
Honey Bee
Apis mellifera
XP_396019
942
106098
S26
E
F
N
K
G
N
W
S
E
A
L
T
C
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
E27
Y
K
D
E
N
Y
D
E
A
I
V
A
Y
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.9
95.5
N.A.
94.9
55.4
N.A.
N.A.
73.5
78.4
71.3
N.A.
34.7
38.1
N.A.
44.1
Protein Similarity:
100
98.5
99.1
97.5
N.A.
98.1
73.9
N.A.
N.A.
81.2
90.3
85
N.A.
58.6
62
N.A.
68.6
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
33.3
N.A.
N.A.
46.6
40
6.6
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
53.3
N.A.
N.A.
66.6
53.3
13.3
N.A.
40
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
17
0
0
0
17
50
75
17
0
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
9
9
9
0
% C
% Asp:
0
0
9
0
0
0
84
0
0
0
9
0
0
0
0
% D
% Glu:
25
0
0
9
9
0
0
9
34
9
0
0
17
0
0
% E
% Phe:
9
9
75
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
9
9
0
0
9
9
0
0
0
0
0
% G
% His:
0
42
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
17
0
9
0
0
0
% I
% Lys:
17
9
0
25
0
0
0
0
42
0
0
0
34
0
17
% K
% Leu:
0
9
0
0
42
0
0
0
0
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
17
0
0
0
9
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
59
0
42
0
9
0
0
0
0
9
0
0
% Q
% Arg:
42
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
17
0
9
0
0
0
0
0
50
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
50
9
17
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% W
% Tyr:
9
17
0
0
0
9
0
67
0
0
0
0
17
9
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _