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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC45B All Species: 36.06
Human Site: Y717 Identified Species: 72.12
UniProt: Q8IWX7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWX7 NP_001028748.1 931 103733 Y717 A F P G E R V Y E V V R P L V
Chimpanzee Pan troglodytes XP_001174363 929 103443 Y715 A F P G E R V Y E V V R P L V
Rhesus Macaque Macaca mulatta XP_001113905 929 103569 Y715 A F P G E R V Y E V V R P L V
Dog Lupus familis XP_537726 943 104653 Y715 A F P G E R V Y E V V R P L V
Cat Felis silvestris
Mouse Mus musculus Q8CGY6 931 103619 Y717 A F P G E R V Y E V V R P L V
Rat Rattus norvegicus Q32PZ3 944 103222 Y731 T F P G E R I Y E V V R P L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415774 1004 111411 Y706 A F P G E R V Y E V V R P L V
Frog Xenopus laevis NP_001087472 927 103492 Y712 A F P G E R V Y E V V R P L V
Zebra Danio Brachydanio rerio NP_705959 934 103829 Y719 A F P G E R I Y E V V R P L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524796 947 105029 L716 S F S G Q R S L D V I R P L L
Honey Bee Apis mellifera XP_396019 942 106098 M713 A F P G Q R I M E V V R P F I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797752 921 101600 L711 A F P G Q R H L E V V R P L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 98.9 95.5 N.A. 94.9 55.4 N.A. N.A. 73.5 78.4 71.3 N.A. 34.7 38.1 N.A. 44.1
Protein Similarity: 100 98.5 99.1 97.5 N.A. 98.1 73.9 N.A. N.A. 81.2 90.3 85 N.A. 58.6 62 N.A. 68.6
P-Site Identity: 100 100 100 100 N.A. 100 86.6 N.A. N.A. 100 100 93.3 N.A. 46.6 66.6 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 100 100 100 N.A. 80 86.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 75 0 0 0 92 0 0 0 0 0 0 % E
% Phe: 0 100 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 25 0 0 0 9 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 17 0 0 0 0 0 92 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 92 0 0 0 0 0 0 0 0 0 100 0 0 % P
% Gln: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 100 0 0 0 0 0 100 0 0 0 % R
% Ser: 9 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 59 0 0 100 92 0 0 0 84 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _