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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHERP All Species: 25.45
Human Site: S104 Identified Species: 46.67
UniProt: Q8IWX8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWX8 NP_006378.3 916 103573 S104 P P A Q G A P S M D E L I Q Q
Chimpanzee Pan troglodytes XP_001172855 914 103883 K101 I P A L W E P K A G R S L E V
Rhesus Macaque Macaca mulatta XP_001112800 916 103706 S104 P P A Q G A P S M D E L I Q Q
Dog Lupus familis XP_852773 1066 119595 S224 P P A Q G A P S M D E L I Q Q
Cat Felis silvestris
Mouse Mus musculus Q8CGZ0 936 106150 S104 T P A Q G T P S M D E L I Q Q
Rat Rattus norvegicus NP_001099534 935 105902 S104 T P A Q G T P S M D E L I Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517825 267 31106
Chicken Gallus gallus XP_001233544 909 103192 S103 P A P Q G T P S V E E L I Q Q
Frog Xenopus laevis NP_001080445 924 104901 P104 P P P Q G A P P I E D L I Q Q
Zebra Danio Brachydanio rerio NP_956368 909 102757 S109 A I P A A A P S M E E L I Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001014589 960 107556 S152 P M A M N L T S Q L E A I K M
Honey Bee Apis mellifera XP_393863 820 90272 N123 T V A Q P L N N V N L A P G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203753 622 69131 G50 P K F G F L F G G E Y Y N Y Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.9 99.6 84.4 N.A. 93.3 93.3 N.A. 27.6 87.5 79.2 73 N.A. 36.9 28.3 N.A. 33
Protein Similarity: 100 96.5 99.6 84.9 N.A. 95.4 95.2 N.A. 28.3 92 86.5 81.5 N.A. 52.1 43.8 N.A. 42.9
P-Site Identity: 100 20 100 100 N.A. 86.6 86.6 N.A. 0 66.6 66.6 60 N.A. 33.3 13.3 N.A. 6.6
P-Site Similarity: 100 33.3 100 100 N.A. 86.6 86.6 N.A. 0 80 86.6 66.6 N.A. 40 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 62 8 8 39 0 0 8 0 0 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 39 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 31 62 0 0 8 0 % E
% Phe: 0 0 8 0 8 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 54 0 0 8 8 8 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 8 0 0 0 70 0 0 % I
% Lys: 0 8 0 0 0 0 0 8 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 8 0 24 0 0 0 8 8 62 8 0 8 % L
% Met: 0 8 0 8 0 0 0 0 47 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 8 0 8 8 0 8 0 0 8 0 0 % N
% Pro: 54 54 24 0 8 0 70 8 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 62 0 0 0 0 8 0 0 0 0 62 62 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 62 0 0 0 8 0 0 0 % S
% Thr: 24 0 0 0 0 24 8 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 16 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _