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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHERP All Species: 30
Human Site: S755 Identified Species: 55
UniProt: Q8IWX8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWX8 NP_006378.3 916 103573 S755 R S S S R S N S R S S K S S G
Chimpanzee Pan troglodytes XP_001172855 914 103883 S753 R S S S R S N S R S S K S S G
Rhesus Macaque Macaca mulatta XP_001112800 916 103706 S755 R S S S R S N S R S S K S S G
Dog Lupus familis XP_852773 1066 119595 S875 R S S S R S N S R S S K S S G
Cat Felis silvestris
Mouse Mus musculus Q8CGZ0 936 106150 S764 R S S S R S S S R S S K S S R
Rat Rattus norvegicus NP_001099534 935 105902 S763 R S S S R S S S R S S K S S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517825 267 31106 F125 D F P P R H P F E R P P Y P H
Chicken Gallus gallus XP_001233544 909 103192 S738 S S R S N S R S S K S S G S Y
Frog Xenopus laevis NP_001080445 924 104901 S738 Q G Q S S S R S N S R S S S R
Zebra Danio Brachydanio rerio NP_956368 909 102757 S738 R S S S H S S S R S S K S S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001014589 960 107556 R787 H R D R S L S R S R S R S R S
Honey Bee Apis mellifera XP_393863 820 90272 P652 R S K S P S P P K K R Y R S K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203753 622 69131 D480 A A P P P A Q D P N D P S L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.9 99.6 84.4 N.A. 93.3 93.3 N.A. 27.6 87.5 79.2 73 N.A. 36.9 28.3 N.A. 33
Protein Similarity: 100 96.5 99.6 84.9 N.A. 95.4 95.2 N.A. 28.3 92 86.5 81.5 N.A. 52.1 43.8 N.A. 42.9
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 6.6 40 40 80 N.A. 13.3 33.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 6.6 40 46.6 86.6 N.A. 26.6 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 0 0 8 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 31 % G
% His: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 8 16 0 54 0 0 8 % K
% Leu: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 8 0 31 0 8 8 0 0 0 0 0 % N
% Pro: 0 0 16 16 16 0 16 8 8 0 8 16 0 8 0 % P
% Gln: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 62 8 8 8 54 0 16 8 54 16 16 8 8 8 31 % R
% Ser: 8 70 54 77 16 77 31 70 16 62 70 16 77 77 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _