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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE1
All Species:
1.82
Human Site:
S475
Identified Species:
4.44
UniProt:
Q8IWY4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWY4
NP_766638.2
988
107910
S475
T
S
S
G
L
G
P
S
C
S
D
A
P
T
T
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
T482
I
H
L
S
S
D
V
T
T
I
R
T
S
V
T
Rhesus Macaque
Macaca mulatta
XP_001108689
995
108761
D476
G
E
F
W
L
S
P
D
A
P
A
T
P
I
K
Dog
Lupus familis
XP_538874
1009
111038
H486
G
N
S
T
N
S
N
H
C
H
E
A
A
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZL8
1018
111587
G505
T
S
S
S
T
G
P
G
C
S
D
A
P
T
T
Rat
Rattus norvegicus
O88281
1574
165428
D672
T
R
S
C
N
P
K
D
G
S
C
S
C
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
T418
H
L
T
S
D
V
S
T
I
R
T
S
V
T
F
Chicken
Gallus gallus
O73775
704
78120
D246
G
S
F
R
C
Q
R
D
T
S
C
G
T
G
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
I497
S
Y
C
P
G
S
G
I
K
T
I
A
T
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
P418
N
L
S
C
D
Q
Q
P
V
A
R
R
K
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.3
89.5
64.8
N.A.
89.2
22.4
N.A.
55.9
21.2
N.A.
64.6
N.A.
N.A.
N.A.
N.A.
43.3
Protein Similarity:
100
76.6
91.6
76.9
N.A.
92.6
31.8
N.A.
67.9
32.7
N.A.
77.2
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
6.6
20
20
N.A.
80
20
N.A.
6.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
20
33.3
N.A.
80
26.6
N.A.
26.6
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
10
40
10
0
10
% A
% Cys:
0
0
10
20
10
0
0
0
30
0
20
0
10
0
0
% C
% Asp:
0
0
0
0
20
10
0
30
0
0
20
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
20
0
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
30
0
0
10
10
20
10
10
10
0
0
10
0
10
0
% G
% His:
10
10
0
0
0
0
0
10
0
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
10
10
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
20
% K
% Leu:
0
20
10
0
20
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
20
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
10
30
10
0
10
0
0
30
0
0
% P
% Gln:
0
0
0
0
0
20
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
10
0
0
10
0
0
10
20
10
0
10
0
% R
% Ser:
10
30
50
30
10
30
10
10
0
40
0
20
10
0
0
% S
% Thr:
30
0
10
10
10
0
0
20
20
10
10
20
20
30
30
% T
% Val:
0
0
0
0
0
10
10
0
10
0
0
0
10
20
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _