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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCUBE1 All Species: 15.15
Human Site: S669 Identified Species: 37.04
UniProt: Q8IWY4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWY4 NP_766638.2 988 107910 S669 S C T P C P S S D G L G L P G
Chimpanzee Pan troglodytes XP_001169046 997 109805 S677 P C P R P G N S G A L K T P E
Rhesus Macaque Macaca mulatta XP_001108689 995 108761 S676 S C T P C P S S D G V G L A G
Dog Lupus familis XP_538874 1009 111038 S691 S C D L C P G S D A H G P L G
Cat Felis silvestris
Mouse Mus musculus Q6NZL8 1018 111587 S699 S C T P C P S S E G L G L A G
Rat Rattus norvegicus O88281 1574 165428 T1019 G A S C D S V T G Q C H C A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510365 931 103588 S612 P C P H S E S S G T Q K T A G
Chicken Gallus gallus O73775 704 78120 Y424 E N T P G S Y Y C T C T M G F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5G872 1010 112158 R693 V C P G P E G R G I P E T A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782645 907 100435 D597 R P G E Y S V D G F Q P C D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.3 89.5 64.8 N.A. 89.2 22.4 N.A. 55.9 21.2 N.A. 64.6 N.A. N.A. N.A. N.A. 43.3
Protein Similarity: 100 76.6 91.6 76.9 N.A. 92.6 31.8 N.A. 67.9 32.7 N.A. 77.2 N.A. N.A. N.A. N.A. 60.1
P-Site Identity: 100 26.6 86.6 53.3 N.A. 86.6 0 N.A. 26.6 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 33.3 93.3 53.3 N.A. 93.3 13.3 N.A. 26.6 20 N.A. 13.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 20 0 0 0 50 0 % A
% Cys: 0 70 0 10 40 0 0 0 10 0 20 0 20 0 0 % C
% Asp: 0 0 10 0 10 0 0 10 30 0 0 0 0 10 0 % D
% Glu: 10 0 0 10 0 20 0 0 10 0 0 10 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % F
% Gly: 10 0 10 10 10 10 20 0 50 30 0 40 0 10 60 % G
% His: 0 0 0 10 0 0 0 0 0 0 10 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 30 0 30 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 20 10 30 40 20 40 0 0 0 0 10 10 10 20 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 20 0 0 0 0 % Q
% Arg: 10 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 40 0 10 0 10 30 40 60 0 0 0 0 0 0 10 % S
% Thr: 0 0 40 0 0 0 0 10 0 20 0 10 30 0 0 % T
% Val: 10 0 0 0 0 0 20 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _