KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF4
All Species:
30.61
Human Site:
S491
Identified Species:
61.21
UniProt:
Q8IWZ8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWZ8
NP_757386.2
645
72471
S491
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Chimpanzee
Pan troglodytes
XP_001142356
641
71959
S487
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Rhesus Macaque
Macaca mulatta
XP_001115248
641
72031
S487
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Dog
Lupus familis
XP_533865
628
70914
S474
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CH02
643
72631
S489
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Rat
Rattus norvegicus
Q68FU8
644
72577
S490
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518067
230
26983
R87
T
W
E
H
Q
L
R
R
M
E
M
D
K
T
R
Chicken
Gallus gallus
XP_425909
649
73577
S495
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730937
832
93822
I678
E
Y
D
S
D
E
D
I
E
G
G
T
W
E
H
Honey Bee
Apis mellifera
XP_393042
903
98662
T749
E
Y
D
S
D
E
E
T
E
G
G
T
W
E
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788058
434
48257
E291
E
H
K
A
R
A
K
E
M
E
D
T
R
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94C11
443
48675
M300
P
R
Q
S
K
D
E
M
P
P
P
A
S
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.7
N.A.
89.6
89.3
N.A.
34.1
75.9
N.A.
N.A.
N.A.
25.2
25.1
N.A.
33.9
Protein Similarity:
100
99.2
98.7
91.7
N.A.
94.4
93.8
N.A.
35.1
84.1
N.A.
N.A.
N.A.
39.9
39.2
N.A.
45.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
N.A.
N.A.
N.A.
53.3
46.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
N.A.
N.A.
66.6
73.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
0
75
0
17
9
67
0
0
0
9
9
0
0
0
% D
% Glu:
25
0
9
59
59
17
17
9
75
17
0
0
0
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
17
75
0
0
0
0
% G
% His:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
75
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
9
0
9
0
0
0
0
0
9
9
9
% K
% Leu:
0
0
0
0
0
9
0
0
0
59
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
9
17
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% P
% Gln:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
9
0
9
9
0
0
0
0
9
0
9
% R
% Ser:
0
59
0
25
0
0
0
59
0
0
0
0
9
0
0
% S
% Thr:
9
0
0
0
0
0
0
9
0
0
0
84
0
9
0
% T
% Val:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
75
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _