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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO1L1 All Species: 2.42
Human Site: T488 Identified Species: 5.33
UniProt: Q8IX06 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IX06 NP_758439 675 73855 T488 S L D G F V E T F K K E L S R
Chimpanzee Pan troglodytes P48778 690 75343 L500 S D L L A L K L I H S T V L D
Rhesus Macaque Macaca mulatta XP_001096198 1215 131336 S1012 E T Q Y M C C S A A A G S V G
Dog Lupus familis XP_533958 1655 172531 S1452 E T Q Y T C C S A A I G S T G
Cat Felis silvestris
Mouse Mus musculus Q7TT28 1213 130772 S1010 E T Q Y M C C S A A V G S V G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516921 311 35095 K132 G F V E T Y I K Y P P F D G N
Chicken Gallus gallus XP_425887 1229 134673 S1026 E T H Y S C C S G A V G S A G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001119888 1207 134661 S1004 E T L Y N C C S G A V G S P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733234 937 105604 P737 Q H R C C Q Q P A G T P G C T
Honey Bee Apis mellifera XP_392195 1145 130995 A917 I I D K Q G F A L Q P Q N C I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790674 215 24370 Y36 K H G D L S G Y M K T M P K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.5 36.2 27.4 N.A. 35 N.A. N.A. 27.5 31.5 N.A. 29.6 N.A. 26.2 24.9 N.A. 20
Protein Similarity: 100 82.6 43.5 32.8 N.A. 42.9 N.A. N.A. 35.4 41.7 N.A. 40 N.A. 39.2 38.9 N.A. 26.6
P-Site Identity: 100 6.6 0 0 N.A. 0 N.A. N.A. 0 0 N.A. 0 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 26.6 6.6 13.3 N.A. 6.6 N.A. N.A. 6.6 13.3 N.A. 6.6 N.A. 6.6 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 37 46 10 0 0 10 0 % A
% Cys: 0 0 0 10 10 46 46 0 0 0 0 0 0 19 0 % C
% Asp: 0 10 19 10 0 0 0 0 0 0 0 0 10 0 19 % D
% Glu: 46 0 0 10 0 0 10 0 0 0 0 10 0 0 0 % E
% Phe: 0 10 0 0 10 0 10 0 10 0 0 10 0 0 0 % F
% Gly: 10 0 10 10 0 10 10 0 19 10 0 46 10 10 46 % G
% His: 0 19 10 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 10 0 10 0 10 0 0 0 10 % I
% Lys: 10 0 0 10 0 0 10 10 0 19 10 0 0 10 0 % K
% Leu: 0 10 19 10 10 10 0 10 10 0 0 0 10 10 0 % L
% Met: 0 0 0 0 19 0 0 0 10 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 10 % N
% Pro: 0 0 0 0 0 0 0 10 0 10 19 10 10 10 0 % P
% Gln: 10 0 28 0 10 10 10 0 0 10 0 10 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 19 0 0 0 10 10 0 46 0 0 10 0 46 10 0 % S
% Thr: 0 46 0 0 19 0 0 10 0 0 19 10 0 10 10 % T
% Val: 0 0 10 0 0 10 0 0 0 0 28 0 10 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 46 0 10 0 10 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _