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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX40
All Species:
17.58
Human Site:
S708
Identified Species:
48.33
UniProt:
Q8IX18
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IX18
NP_078888.3
779
88560
S708
E
F
N
A
H
D
L
S
S
V
A
R
R
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105308
828
93773
S757
E
F
N
A
H
D
L
S
S
V
A
R
R
E
V
Dog
Lupus familis
XP_537699
857
96750
S786
E
F
N
A
H
D
L
S
S
V
A
R
R
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PE54
779
88512
S708
E
L
N
A
H
D
L
S
S
V
A
R
R
E
M
Rat
Rattus norvegicus
Q5XI69
779
88496
S708
E
L
N
A
H
D
L
S
S
V
A
R
R
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510067
755
85770
L684
H
E
I
D
A
Y
E
L
S
S
V
A
R
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XH12
748
85094
R677
H
E
F
S
V
S
E
R
S
C
I
R
I
V
S
Zebra Danio
Brachydanio rerio
XP_698769
735
83328
H665
K
D
L
L
P
K
L
H
E
I
D
V
Y
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O17438
455
51461
F385
A
D
E
A
K
M
R
F
A
H
I
D
G
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.4
89.7
N.A.
97.5
97.5
N.A.
74
N.A.
25.2
63
N.A.
N.A.
N.A.
N.A.
28.1
Protein Similarity:
100
N.A.
92.3
90.3
N.A.
99
98.9
N.A.
85.8
N.A.
47.7
78.3
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
20
N.A.
20
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
67
12
0
0
0
12
0
56
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
23
0
12
0
56
0
0
0
0
12
12
0
12
0
% D
% Glu:
56
23
12
0
0
0
23
0
12
0
0
0
0
78
12
% E
% Phe:
0
34
12
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
23
0
0
0
56
0
0
12
0
12
0
0
0
0
12
% H
% Ile:
0
0
12
0
0
0
0
0
0
12
23
0
12
0
0
% I
% Lys:
12
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
23
12
12
0
0
67
12
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
23
% M
% Asn:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
12
0
0
0
67
67
0
0
% R
% Ser:
0
0
0
12
0
12
0
56
78
12
0
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
56
12
12
0
12
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _