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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM178A All Species: 13.33
Human Site: S99 Identified Species: 41.9
UniProt: Q8IX21 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IX21 NP_060591.3 1173 131873 S99 K L S S P K E S K P K R V P P
Chimpanzee Pan troglodytes XP_001168969 1173 132024 S99 K L S S P K K S K P K R V P P
Rhesus Macaque Macaca mulatta XP_001108956 1171 132181 S99 K L S S P K K S K P K R V P P
Dog Lupus familis XP_850567 1170 131556 S99 K L S S P K K S K P K R V P S
Cat Felis silvestris
Mouse Mus musculus Q6P9P0 1278 143951 L99 K L S S P K K L K P K R M S S
Rat Rattus norvegicus NP_001128084 1134 126682 K99 L S S P K K P K P K R M S S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512094 973 110695
Chicken Gallus gallus XP_421726 750 84767
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.7 90.5 N.A. 77.7 80.6 N.A. 40.3 31.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 98 94.5 N.A. 83.4 86.3 N.A. 56.2 45 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 86.6 N.A. 66.6 13.3 N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 80 20 N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 63 0 0 0 13 75 50 13 63 13 63 0 0 0 0 % K
% Leu: 13 63 0 0 0 0 0 13 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 13 13 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 13 63 0 13 0 13 63 0 0 0 50 38 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 13 63 0 0 0 % R
% Ser: 0 13 75 63 0 0 0 50 0 0 0 0 13 25 25 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _